Key Clinical Points Postmenopausal Osteoporosis Fragility fractures are very common
among postmenopausal women and are associated with increased morbidity, mortality, and …

An update is available for this article. Background: The prevalence of osteoporosis is
increasing in the United States. Purpose: To evaluate low bone mass and osteoporosis …

An update is available for this article. Description: This guideline updates the 2017 American
College of Physicians (ACP) recommendations on pharmacologic treatment of primary …

Importance Observational (nonexperimental) studies that aim to emulate a randomized trial
(ie, the target trial) are increasingly informing medical and policy decision-making, but it is …

Osteoporosis (OP) is characterized by decreased trabecular bone volume and
microarchitectural deterioration in the medullary cavity. Urolithin A (UA) is a biologically …

Background It is unknown whether stop** renin-angiotensin system (RAS) inhibitor
therapy in patients with advanced CKD affects outcomes. Methods We studied patients …

Target trial emulation has drastically improved the quality of observational studies
investigating the effects of interventions. Its ability to prevent avoidable biases that have …

Denosumab is a potent antiresorptive agent that substantially increases bone mineral
density and reduces fracture rates at all skeletal sites for as long as it is administered …

Background and aim. The review aimed to summarize advances in the topic of endocrine
diseases and coronavirus disease 2019 (COVID-19). Methods. Scientific and institutional …

Objective To identify the optimal estimated glomerular filtration rate (eGFR) at which to
initiate dialysis in people with advanced chronic kidney disease. Design Nationwide …