Essential genes are critical for the growth and survival of any organism. The machine
learning approach complements the experimental methods to minimize the resources …

Genes that are thought to be critical for the survival of organisms or cells are called essential
genes. The prediction of essential genes and their products (essential proteins) is of great …

Background and scope Nowadays, centrality analysis has become a principal method for
identifying essential proteins in biological networks. Here we present CytoNCA, a Cytoscape …

Background. Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for
the treatment of ulcerative colitis (UC). In this study, we aimed to identify its molecular target …

Various disciplines are trying to solve one of the most noteworthy queries and broadly used
concepts in biology, essentiality. Centrality is a primary index and a promising method for …

The treatment of cognitive impairment in schizophrenia is an unaddressed need due to the
absence of novel treatments. Recent studies demonstrated that fingolimod and siponimod …

Essential proteins are indispensable for the survival or reproduction of an organism.
Identification of essential proteins is not only necessary for the understanding of the minimal …

Essential proteins are indispensable for cellular life. It is of great significance to identify
essential proteins that can help us understand the minimal requirements for cellular life and …

Prediction of essential proteins which are crucial to an organism's survival is important for
disease analysis and drug design, as well as the understanding of cellular life. The majority …

With the continuing development and improvement of genome-wide techniques, a great
number of candidate genes are discovered. How to identify the most likely disease genes …