Marine pharmacology in 2003–2004: anti-tumour and cytotoxic compounds

AMS Mayer, KR Gustafson - European Journal of Cancer, 2006 - Elsevier
During 2003 and 2004, marine pharmacology research directed towards the discovery and
development of novel anti-tumour agents was published in 163 peer-reviewed articles. The …

The phylum Bryozoa: From biology to biomedical potential

ML Ciavatta, F Lefranc, LM Vieira, R Kiss, M Carbone… - Marine drugs, 2020 - mdpi.com
Less than one percent of marine natural products characterized since 1963 have been
obtained from the phylum Bryozoa which, therefore, still represents a huge reservoir for the …

Green tea polyphenol (−)‐epigallocatechin‐3‐gallate inhibits cyclooxygenase‐2 expression in colon carcinogenesis

G Peng, DA Dixon, SJ Muga, TJ Smith… - … in cooperation with …, 2006 - Wiley Online Library
Tea, one of the most widely consumed beverages worldwide, has been shown to have anti‐
cancer activity in various cancers including colon cancer. It has been demonstrated that …

[LLIBRE][B] Marine Pharmacognosy: Trends and Applications

SK Kim - 2012 - books.google.com
Diverse and abundant, marine-derived bioactive compounds offer a plethora of
pharmacologically active agents with the potential to produce valuable therapeutic entities …

Lymphocytic choriomeningitis virus (LCMV) infection of macaques: a model for Lassa fever

JC Zapata, CD Pauza, MM Djavani, JD Rodas… - Antiviral research, 2011 - Elsevier
Arenaviruses such as Lassa fever virus (LASV) and lymphocytic choriomeningitis virus
(LCMV) are benign in their natural reservoir hosts, and can occasionally cause severe viral …

Alternate NF-κB-independent signaling reactivation of latent HIV-1 provirus

C Acchioni, AL Remoli, G Marsili, M Acchioni… - Journal of …, 2019 - journals.asm.org
Current combination antiretroviral therapies (cART) are unable to eradicate HIV-1 from
infected individuals because of the establishment of proviral latency in long-lived cellular …

The action of the mast cell product tryptase on cyclooxygenase-2 (COX2) and subsequent fibroblast proliferation involves activation of the extracellular signal …

MB Frungieri, M Albrecht, R Raemsch, A Mayerhofer - Cellular signalling, 2005 - Elsevier
The mast cell product tryptase, via protease-activated receptor 2 (PAR2), induces
cyclooxygenase-2 (COX2) and 15-deoxy-prostaglandin J2 (15d-PGJ2) synthesis. 15d-PGJ2 …

Novel marine-derived anti-cancer agents

TE Adrian - Current pharmaceutical design, 2007 - ingentaconnect.com
There is an immense diversity of marine plants and animals from which an estimated 14,000
pharmacologically active compounds have been isolated. However, in terms of clinically …

Marine derived macrolide bryostatin 4 inhibits the TGF-β signaling pathway against acute erythroleukemia

YY Kou, J Liu, YT Chang, LY Liu, F Sun, YL Li… - Cellular Oncology, 2024 - Springer
Purpose Acute erythroleukemia (AEL) is a rare and highly aggressive subtype of acute
myeloid leukemia (AML) with an extremely poor prognosis when treated with available …

[PDF][PDF] Immunohistochemical expression of the cyclooxygenase-2 (COX-2) in gastric cancer. The correlations with the tumor angiogenesis and patients' survival

D Lazar, S Taban, C Ardeleanu, C Simionescu… - Rom J Morphol …, 2008 - rjme.ro
Introduction: The mechanisms by which COX-2 contributes to the carcinogenesis are not
known until present. It seems that the COX-2 enzyme stimulates the cell proliferation, inhibits …