Stimuli‐responsive biomaterials: scaffolds for stem cell control

A Gelmi, CE Schutt - Advanced Healthcare Materials, 2021 - Wiley Online Library
Stem cell fate is closely intertwined with microenvironmental and endogenous cues within
the body. Recapitulating this dynamic environment ex vivo can be achieved through …

Stimuli-responsive biomaterials: smart avenue toward 4D bioprinting

M Rahimnejad, S Jahangiri… - Critical reviews in …, 2024 - Taylor & Francis
Abstract 3D bioprinting is an advanced technology combining cells and bioactive molecules
within a single bioscaffold; however, this scaffold cannot change, modify or grow in response …

Sonogenetics is a non-invasive approach to activating neurons in Caenorhabditis elegans

S Ibsen, A Tong, C Schutt, S Esener… - Nature …, 2015 - nature.com
A major challenge in neuroscience is to reliably activate individual neurons, particularly
those in deeper brain regions. Current optogenetic approaches require invasive surgical …

[HTML][HTML] Microbubble–nanoparticle complexes for ultrasound-enhanced cargo delivery

R Chapla, KT Huynh, CE Schutt - Pharmaceutics, 2022 - mdpi.com
Targeted delivery of therapeutics to specific tissues is critically important for reducing
systemic toxicity and optimizing therapeutic efficacy, especially in the case of cytotoxic …

Enhancing targeted therapy in breast cancer by ultrasound-responsive nanocarriers

IA Edwards, F De Carlo, J Sitta, W Varner… - International Journal of …, 2023 - mdpi.com
Currently, the response to cancer treatments is highly variable, and severe side effects and
toxicity are experienced by patients receiving high doses of chemotherapy, such as those …

A magnetic bead-based sensor for the quantification of multiple prostate cancer biomarkers

JV Jokerst, Z Chen, L Xu, R Nolley, E Chang… - PLoS …, 2015 - journals.plos.org
Novel biomarker assays and upgraded analytical tools are urgently needed to accurately
discriminate benign prostatic hypertrophy (BPH) from prostate cancer (CaP). To address this …

Nanoscale Ultrasound‐Switchable FRET‐Based Liposomes for Near‐Infrared Fluorescence Imaging in Optically Turbid Media

Q Zhang, SP Morgan, ML Mather - Small, 2017 - Wiley Online Library
A new approach for fluorescence imaging in optically turbid media centered on the use of
nanoscale ultrasound‐switchable FRET‐based liposome contrast agents is reported …

Remote-Controlled Gene Delivery in Coaxial 3D-Bioprinted Constructs using Ultrasound-Responsive Bioinks

MK Lowrey, H Day, KJ Schilling, KT Huynh… - Cellular and Molecular …, 2024 - Springer
Introduction Coaxial 3D bioprinting has advanced the formation of tissue constructs that
recapitulate key architectures and biophysical parameters for in-vitro disease modeling and …

Ultrasound induced fluorescence of nanoscale liposome contrast agents

Q Zhang, SP Morgan, P O'Shea, ML Mather - Plos one, 2016 - journals.plos.org
A new imaging contrast agent is reported that provides an increased fluorescent signal upon
application of ultrasound (US). Liposomes containing lipids labelled with pyrene were …

Optical detection of harmonic oscillations in fluorescent dye-loaded microbubbles ensonified by ultrasound

CE Schutt, S Ibsen, M Benchimol, M Hsu, S Esener - Optics letters, 2015 - opg.optica.org
A new optical contrast agent has been developed by exposing dye-loaded microbubbles to
a rapidly-cooled thermal treatment to homogenize the dye distribution across the surface …