Dietary natural products as inhibitors of α-amylase and α-glucosidase: an updated review of ligand-receptor correlations validated by docking studies
M Rangel-Galván, Y Pacheco-Hernández… - Food Bioscience, 2024 - Elsevier
A therapeutic strategy to treat Type 2 diabetes mellitus (T2D) is focused on controlling
postprandial glucose levels by inhibiting α-amylase and α-glucosidase. These enzymes are …
postprandial glucose levels by inhibiting α-amylase and α-glucosidase. These enzymes are …
Metal complexes of fluoroquinolones with selected transition metals, their synthesis, characterizations, and therapeutic applications
Fluoroquinolones (FQs) are broad-spectrum antibiotics which are frequently used against
different diseases caused by pathogens. Due to low toxicity and high biological potential …
different diseases caused by pathogens. Due to low toxicity and high biological potential …
Identification of a novel α-amylase inhibitory activity peptide from quinoa protein hydrolysate
H Zhou, B Safdar, H Li, L Yang, Z Ying, X Liu - Food Chemistry, 2023 - Elsevier
Abstract α-Amylase inhibitory activity plays an important role in reducing blood glucose.
Food-derived α-amylase inhibitors have attracted significant attention due to their safety …
Food-derived α-amylase inhibitors have attracted significant attention due to their safety …
Structure-activity relationships and the underlying mechanism of α-amylase inhibition by hyperoside and quercetin: Multi-spectroscopy and molecular docking …
H Shen, J Wang, J Ao, Y Hou, M **, Y Cai, M Li… - Spectrochimica Acta Part …, 2023 - Elsevier
Inhibiting the activity of α-amylase has been considered an effective strategy to manage
hyperglycemia. Hyperoside and quercetin are the main natural flavonoids in various plants …
hyperglycemia. Hyperoside and quercetin are the main natural flavonoids in various plants …
Chemical Composition, Antibacterial, Antifungal and Antidiabetic Activities of Ethanolic Extracts of Opuntia dillenii Fruits Collected from Morocco
Opuntia dillenii (Ker Gawl.) Haw. belongs to the Cactaceae family and is native to the arid
and semi‐arid regions of Mexico and the southern United States. O. dillenii are now used as …
and semi‐arid regions of Mexico and the southern United States. O. dillenii are now used as …
Characterization of a surfactant-stable α-amylase produced by solid-state fermentation of cassava (Manihot esculenta Crantz) tubers using Rhizopus oligosporus …
Abstract α-Amylase is a foremost hydrolytic enzyme used for various industrial processes. In
the present study, Rhizopus oligosporus α-amylase (ROAA) produced during solid state …
the present study, Rhizopus oligosporus α-amylase (ROAA) produced during solid state …
Anti-obesity, antioxidant and in silico evaluation of Justicia carnea bioactive compounds as potential inhibitors of an enzyme linked with obesity: Insights from kinetics …
Obesity is a global health problem characterized by excessive fat deposition in adipose
tissues and can be managed by targeting pancreatic lipase (PL) activity. In the present …
tissues and can be managed by targeting pancreatic lipase (PL) activity. In the present …
Mechanistic study on the inhibition of α‐amylase and α‐glucosidase using the extract of ultrasound‐treated coffee leaves
Y Sun, Q Cao, Y Huang, T Lu, H Ma… - Journal of the Science …, 2024 - Wiley Online Library
Background Our previous studies have shown that ultrasound‐treated γ‐aminobutyric acid
(GABA)‐rich coffee leaves have higher angiotensin‐I‐converting enzyme inhibitory activity …
(GABA)‐rich coffee leaves have higher angiotensin‐I‐converting enzyme inhibitory activity …
Potential lipase inhibitor from underutilized part of Andrographis paniculata: targeted isolation and mechanism of inhibition
P Gaur, F Khan, K Shanker - Industrial Crops and Products, 2023 - Elsevier
Pancreatic lipase (PL) plays a vital role in lipid metabolism-associated disorders, especially
obesity. The present study demonstrates the targeted isolation of biologically active …
obesity. The present study demonstrates the targeted isolation of biologically active …
α-Amylase inhibition, anti-glycation property and characterization of the binding interaction of citric acid with α-amylase using multiple spectroscopic, kinetics and …
The quest to suppress complications associated with diabetes mellitus is ever increasing,
while food additives and preservatives are currently being considered to play additional …
while food additives and preservatives are currently being considered to play additional …