Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …

Although the role of ferroptosis in killing tumor cells is well established, recent studies
indicate that ferroptosis inducers also sabotage anti-tumor immunity by killing neutrophils …

Genes that are subject to genomic imprinting in mammals are preferentially expressed from
a single parental allele. This imprinted expression of a small number of genes is crucial for …

The placenta has evolved in eutherian mammals primarily to provide nutrients for the
develo** fetus. The genetic control of the regulation of supply and demand for maternal …

Cells of the trophoblast lineage make up the epithelial compartment of the placenta, and
their rapid development is essential for the establishment and maintenance of pregnancy. A …

Imprinted genes play important roles in development, and most are clustered in large
domains. Their allelic repression is regulated by 'imprinting control regions'(ICRs), which are …

Imprinted genes control fetal and placental growth in mice and in rare human syndromes,
but the role of these genes in sporadic intrauterine growth restriction (IUGR) is less well …

Assisted reproductive technologies (ART) are associated with several complications
including low birth weight, abnormal placentation and increased risk for rare imprinting …

The preimplantation mammalian embryo from different species appears sensitive to the
environment in which it develops, either in vitro or in vivo, for example, in response to culture …