Simple Summary When male mice are kept in groups at animal facilities, aggressive
interactions between cage mates are not uncommon. Systematically reviewing previous …

Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

Laboratory rodent housing often fails to meet rodents' behavioral and physiological needs.
We previously found that compared to well-resourced (often called 'enriched') housing …

The manner in which laboratory rodents are housed is driven by economics (minimal use of
space and resources), ergonomics (ease of handling and visibility of animals), hygiene, and …

Controlling aggression is a crucial skill in social species like rodents and humans and has
been associated with anterior cingulate cortex (ACC). Here, we directly link the failed …

Injurious home-cage aggression (fighting) in mice affects both animal welfare and scientific
validity. It is arguably the most common potentially preventable morbidity in mouse facilities …

Background Intracellular deposition of alpha‐synuclein (α‐syn) as Lewy bodies and Lewy
neurites is a central event in the pathogenesis of Parkinson's disease (PD) and other α …

The laboratory mouse is the most prevalent animal used in experimental procedures in the
biomedical and behavioural sciences. Yet, many scientists fail to consider the animals' …

Background: Social dominance status (eg, dominant or subordinate) is often associated with
individual differences in behavior and physiology but is largely neglected in experimental …

Conventional housing for laboratory mice limits the expression of species-specific
behaviours and restricts the control over their environment, thus failing to guarantee the …