Dendritic-cell trafficking to lymph nodes through lymphatic vessels
Antigen-presenting dendritic cells often acquire foreign antigens in peripheral tissues such
as the skin. Optimal encounter with naive T cells for the presentation of these antigens …
as the skin. Optimal encounter with naive T cells for the presentation of these antigens …
Fibroblasts as confederates of the immune system
D Correa‐Gallegos, D Jiang… - Immunological …, 2021 - Wiley Online Library
Fibroblastic stromal cells are as diverse, in origin and function, as the niches they fashion in
the mammalian body. This cellular variety impacts the spectrum of responses elicited by the …
the mammalian body. This cellular variety impacts the spectrum of responses elicited by the …
CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions
L Ohl, M Mohaupt, N Czeloth, G Hintzen, Z Kiafard… - Immunity, 2004 - cell.com
The CC chemokine receptor CCR7 has been identified as a key regulator of homeostatic B
and T cell trafficking to secondary lymphoid organs. Data presented here demonstrate that …
and T cell trafficking to secondary lymphoid organs. Data presented here demonstrate that …
Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
F Sallusto, P Schaerli, P Loetscher… - European journal of …, 1998 - Wiley Online Library
Dendritic cells (DC) migrate into inflamed peripheral tissues where they capture antigens
and, following maturation, to lymph nodes where they stimulate T cells. To gain insight into …
and, following maturation, to lymph nodes where they stimulate T cells. To gain insight into …
Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from …
H Saeki, AM Moore, MJ Brown… - The Journal of …, 1999 - journals.aai.org
Dendritic cells (DCs) emigrate to regional lymph nodes (LNs) during immune responses via
afferent lymphatic channels. Secondary lymphoid-tissue chemokine (SLC), a CC …
afferent lymphatic channels. Secondary lymphoid-tissue chemokine (SLC), a CC …
Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes
Antigen transport from the airway mucosa to the thoracic lymph nodes (TLNs) was studied in
vivo by intratracheal instillation of fluorescein isothiocyanate (FITC)-conjugated …
vivo by intratracheal instillation of fluorescein isothiocyanate (FITC)-conjugated …
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin
M Gunawan, N Venkatesan, JT Loh, JF Wong… - Nature …, 2015 - nature.com
A cytosolic role for the histone methyltransferase Ezh2 in regulating lymphocyte activation
has been suggested, but the molecular mechanisms underpinning this extranuclear function …
has been suggested, but the molecular mechanisms underpinning this extranuclear function …
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin
G Ratzinger, P Stoitzner, S Ebner, MB Lutz… - The Journal of …, 2002 - journals.aai.org
Dendritic cells migrate from the skin to the draining lymph nodes. They transport
immunogenic MHC-peptide complexes, present them to Ag-specific T cells in the T areas …
immunogenic MHC-peptide complexes, present them to Ag-specific T cells in the T areas …
[HTML][HTML] Cancer dissemination—lessons from leukocytes
CD Madsen, E Sahai - Developmental cell, 2010 - cell.com
Cancer cells can move through tissues in a variety of different ways. In some cases, an
epithelial-to-mesenchymal transition enables cancer cells to acquire fibroblast-like migratory …
epithelial-to-mesenchymal transition enables cancer cells to acquire fibroblast-like migratory …