[HTML][HTML] Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: a systematic review

D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

[HTML][HTML] Amyloid precursor protein and Alzheimer's disease

KS Orobets, AL Karamyshev - International journal of molecular sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is one of the most common neurodegenerative disorders
associated with age or inherited mutations. It is characterized by severe dementia in the late …

The theta rhythm of the hippocampus: from neuronal and circuit mechanisms to behavior

A Nuñez, W Buño - Frontiers in cellular neuroscience, 2021 - frontiersin.org
This review focuses on the neuronal and circuit mechanisms involved in the generation of
the theta (θ) rhythm and of its participation in behavior. Data have accumulated indicating …

Respiration-entrained brain rhythms are global but often overlooked

ABL Tort, J Brankačk, A Draguhn - Trends in neurosciences, 2018 - cell.com
We revisit recent evidence showing that nasal respiration entrains oscillations at the same
frequency as breathing in several regions of the rodent brain. Moreover, respiration …

What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons

C Babiloni, K Blinowska, L Bonanni, A Cichocki… - Neurobiology of …, 2020 - Elsevier
Electrophysiology provides a real-time readout of neural functions and network capability in
different brain states, on temporal (fractions of milliseconds) and spatial (micro, meso, and …

Organization of prefrontal network activity by respiration-related oscillations

J Biskamp, M Bartos, JF Sauer - Scientific reports, 2017 - nature.com
The medial prefrontal cortex (mPFC) integrates information from cortical and sub-cortical
areas and contributes to the planning and initiation of behaviour. A potential mechanism for …

Selective entrainment of gamma subbands by different slow network oscillations

W Zhong, M Ciatipis, T Wolfenstetter… - Proceedings of the …, 2017 - pnas.org
Theta oscillations (4–12 Hz) are thought to provide a common temporal reference for the
exchange of information among distant brain networks. On the other hand, faster gamma …

Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain

ABL Tort, S Ponsel, J Jessberger, Y Yanovsky… - Scientific reports, 2018 - nature.com
Slow brain oscillations are usually coherent over long distances and thought to link
distributed cell assemblies. In mice, theta (5–10 Hz) stands as one of the most studied slow …

Enhanced gamma activity and cross-frequency interaction of resting-state electroencephalographic oscillations in patients with Alzheimer's disease

J Wang, Y Fang, X Wang, H Yang, X Yu… - Frontiers in aging …, 2017 - frontiersin.org
Cognitive impairment, functional decline and behavioral symptoms that characterize
Alzheimer's disease (AD) are associated with perturbations of the neuronal network. The …

Unsupervised excitation: GABAergic dysfunctions in Alzheimer's disease

EA Giovannetti, M Fuhrmann - Brain research, 2019 - Elsevier
Alzheimer's disease (AD) is characterized by the classical hallmarks of Aβ-deposition and
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …