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[HTML][HTML] Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: a systematic review
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …
affecting around 46 million people worldwide but few treatments are currently available. The …
[HTML][HTML] Amyloid precursor protein and Alzheimer's disease
KS Orobets, AL Karamyshev - International journal of molecular sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is one of the most common neurodegenerative disorders
associated with age or inherited mutations. It is characterized by severe dementia in the late …
associated with age or inherited mutations. It is characterized by severe dementia in the late …
The theta rhythm of the hippocampus: from neuronal and circuit mechanisms to behavior
A Nuñez, W Buño - Frontiers in cellular neuroscience, 2021 - frontiersin.org
This review focuses on the neuronal and circuit mechanisms involved in the generation of
the theta (θ) rhythm and of its participation in behavior. Data have accumulated indicating …
the theta (θ) rhythm and of its participation in behavior. Data have accumulated indicating …
Respiration-entrained brain rhythms are global but often overlooked
We revisit recent evidence showing that nasal respiration entrains oscillations at the same
frequency as breathing in several regions of the rodent brain. Moreover, respiration …
frequency as breathing in several regions of the rodent brain. Moreover, respiration …
What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons
Electrophysiology provides a real-time readout of neural functions and network capability in
different brain states, on temporal (fractions of milliseconds) and spatial (micro, meso, and …
different brain states, on temporal (fractions of milliseconds) and spatial (micro, meso, and …
Organization of prefrontal network activity by respiration-related oscillations
The medial prefrontal cortex (mPFC) integrates information from cortical and sub-cortical
areas and contributes to the planning and initiation of behaviour. A potential mechanism for …
areas and contributes to the planning and initiation of behaviour. A potential mechanism for …
Selective entrainment of gamma subbands by different slow network oscillations
W Zhong, M Ciatipis, T Wolfenstetter… - Proceedings of the …, 2017 - pnas.org
Theta oscillations (4–12 Hz) are thought to provide a common temporal reference for the
exchange of information among distant brain networks. On the other hand, faster gamma …
exchange of information among distant brain networks. On the other hand, faster gamma …
Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain
ABL Tort, S Ponsel, J Jessberger, Y Yanovsky… - Scientific reports, 2018 - nature.com
Slow brain oscillations are usually coherent over long distances and thought to link
distributed cell assemblies. In mice, theta (5–10 Hz) stands as one of the most studied slow …
distributed cell assemblies. In mice, theta (5–10 Hz) stands as one of the most studied slow …
Enhanced gamma activity and cross-frequency interaction of resting-state electroencephalographic oscillations in patients with Alzheimer's disease
Cognitive impairment, functional decline and behavioral symptoms that characterize
Alzheimer's disease (AD) are associated with perturbations of the neuronal network. The …
Alzheimer's disease (AD) are associated with perturbations of the neuronal network. The …
Unsupervised excitation: GABAergic dysfunctions in Alzheimer's disease
EA Giovannetti, M Fuhrmann - Brain research, 2019 - Elsevier
Alzheimer's disease (AD) is characterized by the classical hallmarks of Aβ-deposition and
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …