Use of zebrafish in drug discovery toxicology

S Cassar, I Adatto, JL Freeman, JT Gamse… - Chemical research in …, 2019 - ACS Publications
Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …

Major contaminants of emerging concern in soils: a perspective on potential health risks

NR Maddela, B Ramakrishnan, D Kakarla… - RSC …, 2022 - pubs.rsc.org
Soil pollution by the contaminants of emerging concern (CECs) or emerging contaminants
deserves attention worldwide because of their toxic health effects and the need for …

[HTML][HTML] A vision for safer food contact materials: Public health concerns as drivers for improved testing

J Muncke, AM Andersson, T Backhaus… - Environment …, 2023 - Elsevier
Food contact materials (FCMs) and food contact articles are ubiquitous in today's globalized
food system. Chemicals migrate from FCMs into foodstuffs, so called food contact chemicals …

[HTML][HTML] Exposure to novel and legacy per-and polyfluoroalkyl substances (PFASs) and associations with type 2 diabetes: A case-control study in East China

X Han, L Meng, G Zhang, Y Li, Y Shi, Q Zhang… - Environment …, 2021 - Elsevier
Associations between per-and polyfluoroalkyl substances (PFASs) and the incidence of type
2 diabetes are controversial in epidemiological studies. In addition, limited data are …

Bioconcentration and metabolic effects of emerging PFOS alternatives in develo** zebrafish

W Tu, R Martínez, L Navarro-Martin… - Environmental …, 2019 - ACS Publications
The novel PFOS alternatives, 6: 2 chlorinated polyfluorinated ether sulfonate (F-53B) and
sodium p-perfluorous nonenoxybenzenesulfonate (OBS), are emerging in the Chinese …

Perfluorooctane sulfonic acid (PFOS) adsorbed to polyethylene microplastics: accumulation and ecotoxicological effects in the clam Scrobicularia plana

N Islam, TG da Fonseca, J Vilke, JM Gonçalves… - Marine environmental …, 2021 - Elsevier
Microplastics are widespread in the marine environment, whereby the uptake of these tiny
particles by organisms, can cause adverse biological responses. Plastic debris also act as a …

A pathway level analysis of PFAS exposure and risk of gestational diabetes mellitus

RL Birru, HW Liang, F Farooq, M Bedi, M Feghali… - Environmental …, 2021 - Springer
Per-and polyfluoroalkyl substances (PFAS) have been found to be associated with
gestational diabetes mellitus (GDM) development, a maternal health disorder in pregnancy …

Associations between exposures to perfluoroalkyl substances and diabetes, hyperglycemia, or insulin resistance: a sco** review

R Margolis, KE Sant - Journal of xenobiotics, 2021 - mdpi.com
Per-and polyfluoroalkyl substances (PFASs) are persistent environmental pollutants that are
commonly found in the human body due to exposures via drinking water, surfactants used in …

Developmental exposures to perfluorooctanesulfonic acid (PFOS) impact embryonic nutrition, pancreatic morphology, and adiposity in the zebrafish, Danio rerio

KE Sant, K Annunziato, S Conlin, G Teicher… - Environmental …, 2021 - Elsevier
Perfluorooctanesulfonic acid (PFOS) is a persistent environmental contaminant previously
found in consumer surfactants and industrial fire-fighting foams. PFOS has been widely …

Plasma concentrations of perfluoroalkyl substances and risk of type 2 diabetes: a prospective investigation among US women

Q Sun, G Zong, D Valvi, F Nielsen… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Emerging evidence suggests that perfluoroalkyl substances (PFASs) are
endocrine disruptors and may contribute to the etiology of type 2 diabetes (T2D), but this …