Purpose Emerging evidence suggests a detrimental prognostic association between
radiation-induced lymphopenia (RIL) and pathologic response, progression-free survival …

There is now strong clinical and preclinical evidence that lymphocytes, for example, CD8+ T
cells, are key effectors of immunotherapy and that irradiation of large blood vessels, the …

Introduction Lymphopenia after radiotherapy has an adverse effect on the patient's outcome.
However, the relationship between radiotherapy dose delivery and lymphopenia is not fully …

Radiation-induced lymphopenia (RIL) is characterized by a significant decrease in the
absolute number of lymphocytes circulating in the blood after radiotherapy. With the major …

Introduction Durvalumab after concurrent chemoradiation (CCRT) for NSCLC improves
survival, but only in a subset of patients. We investigated the effect of severe radiation …

Purpose Lymphocytes play an important role in antitumor immunity; however, they are also
especially vulnerable to depletion during chemoradiation therapy (CRT). The purpose of this …

Chimeric antigen receptor (CAR)-T cells have demonstrated significant improvements in the
treatment of refractory B-cell malignancies that previously showed limited survival. In …

Background The aim of the study was to analyze the relationship between pretreatment
inflammatory biomarkers (IBs) and survival outcomes for patients with esophageal …

Esophageal cancer remains one of the leading causes of death from cancer across the
world despite advances in multimodality therapy. Although early-stage disease can often be …

Despite technological advances in radiotherapy and cancer treatment, patients still
experience adverse effects. Proton therapy has emerged as a valuable radiotherapy …