Parasitic diseases still constitute a major global health problem affecting billions of people
around the world. These diseases are capable of becoming chronic and result in high …

Leishmaniasis is a neglected tropical disease and remains a global concern for healthcare.
It is caused by an opportunistic protozoan parasite belonging to the genus Leishmania and …

Background Photosynthetic euglenids are major contributors to fresh water ecosystems.
Euglena gracilis in particular has noted metabolic flexibility, reflected by an ability to thrive in …

The development of an immunogenic, effective, and safe vaccine is essential as an
alternative for disease control. The present study aimed to evaluate the immunogenicity and …

Canine visceral leishmaniasis is an increasingly important public health problem. Dogs
infected by Leishmania infantum are the main domestic reservoir of the parasite and play a …

Background Majority of individuals with history of visceral leishmaniasis (VL) exhibit strong
immunity to re-infection, however, the mechanism of resistance is poorly understood. It is …

Spain has one of the world's largest pools of organ donors and is a global leader in terms of
the number of transplants it performs. The current outbreak of leishmaniasis in Fuenlabrada …

The development of prophylactic vaccines is important in preventing and controlling
diseases such as visceral leishmaniasis (VL), in addition to being an economic measure for …

Dogs are the main reservoir of zoonotic visceral leishmaniasis. Vaccination is a promising
approach to help control leishmaniasis and to interrupt transmission of the Leishmania …

No field method exists for identifying asymptomatic individuals in areas where Leishmania
infantum is endemic. This work reports that, 24 h after stimulating whole blood with soluble …