Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review

A Lisibach, V Benelli, MG Ceppi… - European journal of …, 2021‏ - Springer
Purpose Older people are at risk of anticholinergic side effects due to changes affecting drug
elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) …

Association of the Drug Burden Index (DBI) exposure with outcomes: A systematic review

BM Liu, L Kouladjian O'Donnell… - Journal of the …, 2024‏ - Wiley Online Library
Abstract Background The Drug Burden Index (DBI) measures an individual's total exposure
to anticholinergic and sedative medications. This systematic review aimed to investigate the …

Association between anticholinergic drug burden and mortality in older people: a systematic review

S Ali, GM Peterson, LR Bereznicki… - European Journal of …, 2020‏ - Springer
Purpose The purpose of the study is to conduct a systematic review of studies examining the
association between anticholinergic burden and mortality in older individuals. Methods A …

The prognostic value of anticholinergic burden measures in relation to mortality in older individuals: a systematic review and meta-analysis

K Graves-Morris, C Stewart, RL Soiza… - Frontiers in …, 2020‏ - frontiersin.org
Background Greater anticholinergic burden (ACB) increases the risk of mortality in older
individuals, yet the strength of this association varies between studies. One possible …

[HTML][HTML] Association between anticholinergic burden and constipation: a systematic review

H Rodríguez-Ramallo, N Báez-Gutiérrez, E Prado-Mel… - Healthcare, 2021‏ - mdpi.com
The association between anticholinergic burden and constipation is not well defined and
documented; for this reason, a systematic review was carried out in five databases (Medline …

A cohort study of anticholinergic medication burden and incident dementia and stroke in older adults

JE Lockery, JC Broder, J Ryan, AC Stewart… - Journal of General …, 2021‏ - Springer
Background Anticholinergic medications may increase risk of dementia and stroke, but
prospective studies in healthy older people are lacking. Objective Compare risk of incident …

The impact of high-risk medications on mortality risk among older adults with polypharmacy: Evidence from the English Longitudinal Study of Ageing

YT Huang, A Steptoe, L Wei, P Zaninotto - BMC medicine, 2021‏ - Springer
Background Polypharmacy is common among older people and is associated with an
increased mortality risk. However, little is known about whether the mortality risk is related to …

Anticholinergic burden in older adult inpatients: patterns from admission to discharge and associations with hospital outcomes

M Herrero-Zazo, R Berry, E Bines… - … Advances in Drug …, 2021‏ - journals.sagepub.com
Background: Anticholinergic medications are associated with adverse outcomes in older
adults and should be prescribed cautiously. We describe the Anticholinergic Risk Scale …

High anticholinergic burden at admission associated with in‐hospital mortality in older patients: a comparison of 19 different anticholinergic burden scales

A Lisibach, G Gallucci, PE Beeler… - Basic & clinical …, 2022‏ - Wiley Online Library
Although no gold standard exists to assess a patient's anticholinergic burden, a review
identified 19 anticholinergic burden scales (ABSs). No study has yet evaluated whether a …

Prehospital anticholinergic burden is associated with delirium but not with mortality in a population of acutely ill medical patients

J Rigor, IR Rato, PM Ferreira, R Pereira… - Journal of the American …, 2020‏ - Elsevier
Objectives Anticholinergic drugs have several side effects, and they have been associated
with adverse outcomes, particularly in older patients. The aim of this study was to analyze …