Manufacturing of non-viral protein nanocages for biotechnological and biomedical applications
Protein nanocages are highly ordered nanometer scale architectures, which are typically
formed by homo-or hetero-self-assembly of multiple monomers into symmetric structures of …
formed by homo-or hetero-self-assembly of multiple monomers into symmetric structures of …
[HTML][HTML] Development of a Two-Component Nanoparticle Vaccine Displaying an HIV-1 Envelope Glycoprotein that Elicits Tier 2 Neutralising Antibodies
K Malebo, J Woodward, P **mba, Q Mkhize, S Cingo… - Vaccines, 2024 - mdpi.com
Despite treatment and other interventions, an effective prophylactic HIV vaccine is still an
essential goal in the control of HIV. Inducing robust and long-lasting antibody responses is …
essential goal in the control of HIV. Inducing robust and long-lasting antibody responses is …
Mitigating the Blurring Effect of CryoEM Averaging on a Flexible and Highly Symmetric Protein Complex through Sub-Particle Reconstruction
DS Suder, S Gonen - International Journal of Molecular Sciences, 2024 - mdpi.com
Many macromolecules are inherently flexible as a feature of their structure and function.
During single-particle CryoEM processing, flexible protein regions can be detrimental to …
During single-particle CryoEM processing, flexible protein regions can be detrimental to …
[HTML][HTML] Quantitative Comparison of Monomeric StayGold Variants Using Protein Nanocages in Living Cells
To standardize comparison of fluorescent proteins and independently determine which
monomeric StayGold variant is best for live microscopy, we analyzed fluorescent protein …
monomeric StayGold variant is best for live microscopy, we analyzed fluorescent protein …