NRF2, a transcription factor for stress response and beyond
F He, X Ru, T Wen - International journal of molecular sciences, 2020 - mdpi.com
Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that regulates the
cellular defense against toxic and oxidative insults through the expression of genes involved …
cellular defense against toxic and oxidative insults through the expression of genes involved …
Immunometabolism: from basic mechanisms to translation
Immunometabolism has emerged as a major mechanism central to adaptive and innate
immune regulation. From early observations that inflammatory cytokines were induced in …
immune regulation. From early observations that inflammatory cytokines were induced in …
NRF2 as a regulator of cell metabolism and inflammation in cancer
Nuclear factor erythroid 2‐related factor 2 (NRF2) is a master transcriptional regulator of
genes whose products defend our cells for toxic and oxidative insults. Although NRF2 …
genes whose products defend our cells for toxic and oxidative insults. Although NRF2 …
[HTML][HTML] Beyond repression of Nrf2: An update on Keap1
Abstract Nrf2 (NFE2L2–nuclear factor (erythroid-derived 2)-like 2) is a transcription factor,
which is repressed by interaction with a redox-sensitive protein Keap1 (Kelch-like ECH …
which is repressed by interaction with a redox-sensitive protein Keap1 (Kelch-like ECH …
[HTML][HTML] AMPK and NRF2: Interactive players in the same team for cellular homeostasis?
E Petsouki, SNS Cabrera, EH Heiss - Free Radical Biology and Medicine, 2022 - Elsevier
NRF2 (Nuclear factor E2 p45‐related factor 2) is a stress responsive transcription factor
lending cells resilience against oxidative, xenobiotic, and also nutrient or proteotoxic insults …
lending cells resilience against oxidative, xenobiotic, and also nutrient or proteotoxic insults …
Redox signaling at the crossroads of human health and disease
Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …
processes with biological activities. Redox homeostasis is a prerequisite for human health …
Dendrobium officinale polysaccharide triggers mitochondrial disorder to induce colon cancer cell death via ROS-AMPK-autophagy pathway
K Zhang, X Zhou, J Wang, Y Zhou, W Qi, H Chen… - Carbohydrate …, 2021 - Elsevier
The homeostasis between mitochondrial function and autophagy is crucial to the
physiological activity of cancer cells, and its mechanism is conducive to the development of …
physiological activity of cancer cells, and its mechanism is conducive to the development of …
The immunometabolic ecosystem in cancer
GR Bantug, C Hess - Nature Immunology, 2023 - nature.com
Our increased understanding of how key metabolic pathways are activated and regulated in
malignant cells has identified metabolic vulnerabilities of cancers. Translating this insight to …
malignant cells has identified metabolic vulnerabilities of cancers. Translating this insight to …
[HTML][HTML] Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes
C Moschandrea, V Kondylis, I Evangelakos, M Herholz… - Nature, 2024 - nature.com
Digested dietary fats are taken up by enterocytes where they are assembled into pre-
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …
Supplying the trip to antibody production—nutrients, signaling, and the programming of cellular metabolism in the mature B lineage
MR Boothby, SK Brookens, AL Raybuck… - Cellular & Molecular …, 2022 - nature.com
The COVID pandemic has refreshed and expanded recognition of the vital role that
sustained antibody (Ab) secretion plays in our immune defenses against microbes and of …
sustained antibody (Ab) secretion plays in our immune defenses against microbes and of …