[HTML][HTML] Pattern formation mechanisms of self-organizing reaction-diffusion systems
Embryonic development is a largely self-organizing process, in which the adult body plan
arises from a ball of cells with initially nearly equal potency. The reaction-diffusion theory first …
arises from a ball of cells with initially nearly equal potency. The reaction-diffusion theory first …
Self-organization in pattern formation
F Schweisguth, F Corson - Developmental cell, 2019 - cell.com
Self-organization is pervasive in development, from symmetry breaking in the early embryo
to tissue patterning and morphogenesis. For a few model systems, the underlying molecular …
to tissue patterning and morphogenesis. For a few model systems, the underlying molecular …
Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids
DA Turner, M Girgin, L Alonso-Crisostomo… - …, 2017 - journals.biologists.com
The establishment of the anteroposterior (AP) axis is a crucial step during animal embryo
development. In mammals, genetic studies have shown that this process relies on signals …
development. In mammals, genetic studies have shown that this process relies on signals …
Two MYB proteins in a self-organizing activator-inhibitor system produce spotted pigmentation patterns
Many organisms exhibit visually striking spotted or striped pigmentation patterns.
Developmental models predict that such spatial patterns can form when a local autocatalytic …
Developmental models predict that such spatial patterns can form when a local autocatalytic …
Stochastic Turing patterns in a synthetic bacterial population
The origin of biological morphology and form is one of the deepest problems in science,
underlying our understanding of development and the functioning of living systems. In 1952 …
underlying our understanding of development and the functioning of living systems. In 1952 …
Agent-based modeling of morphogenetic systems: Advantages and challenges
The complexity of morphogenesis poses a fundamental challenge to understanding the
mechanisms governing the formation of biological patterns and structures. Over the past …
mechanisms governing the formation of biological patterns and structures. Over the past …
Modern perspectives on near-equilibrium analysis of Turing systems
In the nearly seven decades since the publication of Alan Turing's work on morphogenesis,
enormous progress has been made in understanding both the mathematical and biological …
enormous progress has been made in understanding both the mathematical and biological …
Turing pattern design principles and their robustness
ST Vittadello, T Leyshon… - … Transactions of the …, 2021 - royalsocietypublishing.org
Turing patterns have morphed from mathematical curiosities into highly desirable targets for
synthetic biology. For a long time, their biological significance was sometimes disputed but …
synthetic biology. For a long time, their biological significance was sometimes disputed but …
A comprehensive network atlas reveals that Turing patterns are common but not robust
Turing patterns (TPs) underlie many fundamental developmental processes, but they
operate over narrow parameter ranges, raising the conundrum of how evolution can ever …
operate over narrow parameter ranges, raising the conundrum of how evolution can ever …
Self-organized BMP signaling dynamics underlie the development and evolution of digit segmentation patterns in birds and mammals
E Grall, C Feregrino, S Fischer… - Proceedings of the …, 2024 - National Acad Sciences
Repeating patterns of synovial joints are a highly conserved feature of articulated digits, with
variations in joint number and location resulting in diverse digit morphologies and limb …
variations in joint number and location resulting in diverse digit morphologies and limb …