Molecular farming–the slope of enlightenment
Molecular farming can be defined as the use of plants to produce recombinant protein
products. The technology is now> 30 years old. The early promise of molecular farming was …
products. The technology is now> 30 years old. The early promise of molecular farming was …
Plants as sources of natural and recombinant anti-cancer agents
JF Buyel - Biotechnology advances, 2018 - Elsevier
Herbal remedies were the first medicines used by humans due to the many
pharmacologically active secondary metabolites produced by plants. Some of these …
pharmacologically active secondary metabolites produced by plants. Some of these …
[HTML][HTML] Plants as factories for human pharmaceuticals: applications and challenges
J Yao, Y Weng, A Dickey, KY Wang - International journal of molecular …, 2015 - mdpi.com
Plant molecular farming (PMF), defined as the practice of using plants to produce human
therapeutic proteins, has received worldwide interest. PMF has grown and advanced …
therapeutic proteins, has received worldwide interest. PMF has grown and advanced …
Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules
Plant cell culture systems were initially explored for use in commercial synthesis of several
high‐value secondary metabolites, allowing for sustainable production that was not limited …
high‐value secondary metabolites, allowing for sustainable production that was not limited …
Plant molecular farming–integration and exploitation of side streams to achieve sustainable biomanufacturing
JF Buyel - Frontiers in plant science, 2019 - frontiersin.org
Plants have unique advantages over other systems such as mammalian cells for the
production of valuable small molecules and proteins. The benefits cited most often include …
production of valuable small molecules and proteins. The benefits cited most often include …
Plant molecular farming: much more than medicines
M Tschofen, D Knopp, E Hood… - Annual Review of …, 2016 - annualreviews.org
Plants have emerged as commercially relevant production systems for pharmaceutical and
nonpharmaceutical products. Currently, the commercially available nonpharmaceutical …
nonpharmaceutical products. Currently, the commercially available nonpharmaceutical …
[HTML][HTML] On the verge of the market–Plant factories for the automated and standardized production of biopharmaceuticals
The market for biopharmaceuticals is dominated by recombinant proteins and is driven
mainly by the development of vaccines and antibodies. Manufacturing predominantly relies …
mainly by the development of vaccines and antibodies. Manufacturing predominantly relies …
Extraction and downstream processing of plant-derived recombinant proteins
Plants offer the tantalizing prospect of low-cost automated manufacturing processes for
biopharmaceutical proteins, but several challenges must be addressed before such goals …
biopharmaceutical proteins, but several challenges must be addressed before such goals …
Challenges and opportunities in the purification of recombinant tagged proteins
The purification of recombinant proteins by affinity chromatography is one of the most
efficient strategies due to the high recovery yields and purity achieved. However, this is …
efficient strategies due to the high recovery yields and purity achieved. However, this is …
Commercial aspects of pharmaceutical protein production in plants
Many different plant-based systems have been used to produce recombinant
pharmaceutical proteins but only a small number have made the leap from an experimental …
pharmaceutical proteins but only a small number have made the leap from an experimental …