40 years after the registration of acyclovir: do we need new anti-herpetic drugs?

A Majewska, B Mlynarczyk-Bonikowska - International journal of …, 2022 - mdpi.com
Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …

Virus-like particles and nanoparticles for vaccine development against HCMV

M Perotti, L Perez - Viruses, 2019 - mdpi.com
Human cytomegalovirus (HCMV) infects more than 70% of the human population worldwide.
HCMV is responsible for high morbidity and mortality in immunocompromised patients and …

[HTML][HTML] Vaccine value profile for cytomegalovirus

SB Boppana, M van Boven, WJ Britt, S Gantt… - Vaccine, 2023 - Elsevier
Cytomegalovirus (CMV) is the most common infectious cause of congenital malformation
and a leading cause of developmental disabilities such as sensorineural hearing loss …

The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spread

AC Gomes, IA Baraniak, A Lankina, Z Moulder… - Nature …, 2023 - nature.com
Vaccination against human cytomegalovirus (CMV) infection remains high priority. A
recombinant form of a protein essential for CMV entry, glycoprotein B (gB), demonstrated …

Myocarditis: causes, mechanisms, and evolving therapies

T Kyaw, G Drummond, A Bobik… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Myocarditis is a severe lymphocyte-mediated inflammatory disorder of the heart,
mostly caused by viruses and immune checkpoint inhibitors (ICIs). Recently, myocarditis as …

[HTML][HTML] Insight for immunotherapy of HCMV infection

X Long, Y Qiu, Z Zhang, M Wu - International journal of biological …, 2021 - ncbi.nlm.nih.gov
Human cytomegalovirus (HCMV), a ubiquitous in humans, has a high prevalence rate.
Young people are susceptible to HCMV infection in develo** countries, while older …

Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV

SJ Theobald, C Kreer, S Khailaie, A Bonifacius… - PLoS …, 2020 - journals.plos.org
Human cytomegalovirus (HCMV) causes serious complications to immune compromised
hosts. Dendritic cells (iDCgB) expressing granulocyte-macrophage colony-stimulating factor …

Common polymorphisms in the glycoproteins of human cytomegalovirus and associated strain-specific immunity

HY Wang, SM Valencia, SP Pfeifer, JD Jensen… - Viruses, 2021 - mdpi.com
Human cytomegalovirus (HCMV), one of the most prevalent viruses across the globe, is a
common cause of morbidity and mortality for immunocompromised individuals. Recent …

A bivalent CMV vaccine formulated with human compatible TLR9 agonist CpG1018 elicits potent cellular and humoral immunity in HLA expressing mice

V Dasari, K Beckett, S Horsefield… - PLoS …, 2022 - journals.plos.org
There is now convincing evidence that the successful development of an effective CMV
vaccine will require improved formulation and adjuvant selection that is capable of inducing …

Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity

M Perotti, J Marcandalli, D Demurtas, F Sallusto… - PLoS …, 2020 - journals.plos.org
Human cytomegalovirus (HCMV) is the primary viral cause of congenital birth defects and
causes significant morbidity and mortality in immune-suppressed transplant recipients …