Guidelines for measuring cardiac physiology in mice

ML Lindsey, Z Kassiri, JAI Virag… - American Journal …, 2018 - journals.physiology.org
Cardiovascular disease is a leading cause of death, and translational research is needed to
understand better mechanisms whereby the left ventricle responds to injury. Mouse models …

Diffusion MRI in the heart

C Mekkaoui, TG Reese, MP Jackowski… - NMR in …, 2017 - Wiley Online Library
Diffusion MRI provides unique information on the structure, organization, and integrity of the
myocardium without the need for exogenous contrast agents. Diffusion MRI in the heart …

In vivo diffusion tensor MRI of the human heart: reproducibility of breath‐hold and navigator‐based approaches

S Nielles‐Vallespin, C Mekkaoui… - Magnetic resonance …, 2013 - Wiley Online Library
The aim of this study was to implement a quantitative in vivo cardiac diffusion tensor imaging
(DTI) technique that was robust, reproducible, and feasible to perform in patients with …

Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip

ML McCain, SP Sheehy, A Grosberg, JA Goss… - Proceedings of the …, 2013 - pnas.org
The lack of a robust pipeline of medical therapeutic agents for the treatment of heart disease
may be partially attributed to the lack of in vitro models that recapitulate the essential …

[HTML][HTML] Diffusion MR tractography of the heart

DE Sosnovik, R Wang, G Dai, TG Reese… - Journal of Cardiovascular …, 2009 - Elsevier
Histological studies have shown that the myocardium consists of an array of crossing helical
fiber tracts. Changes in myocardial fiber architecture occur in ischemic heart disease and …

Higher-order motion-compensation for in vivo cardiac diffusion tensor imaging in rats

CL Welsh, EVR DiBella, EW Hsu - IEEE transactions on …, 2015 - ieeexplore.ieee.org
Motion of the heart has complicated in vivo applications of cardiac diffusion MRI and
diffusion tensor imaging (DTI), especially in small animals such as rats where ultra-high …

Spin echo versus stimulated echo diffusion tensor imaging of the in vivo human heart

C von Deuster, CT Stoeck, M Genet… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To compare signal‐to‐noise ratio (SNR) efficiency and diffusion tensor metrics of
cardiac diffusion tensor map** using acceleration‐compensated spin‐echo (SE) and …

An orthotropic viscoelastic model for the passive myocardium: continuum basis and numerical treatment

O Gültekin, G Sommer, GA Holzapfel - Computer methods in …, 2016 - Taylor & Francis
This study deals with the viscoelastic constitutive modeling and the respective computational
analysis of the human passive myocardium. We start by recapitulating the locally orthotropic …

Dual-phase cardiac diffusion tensor imaging with strain correction

CT Stoeck, A Kalinowska, C Von Deuster, J Harmer… - PloS one, 2014 - journals.plos.org
Purpose In this work we present a dual-phase diffusion tensor imaging (DTI) technique that
incorporates a correction scheme for the cardiac material strain, based on 3D myocardial …

Quantitative tracking of edema, hemorrhage, and microvascular obstruction in subacute myocardial infarction in a porcine model by MRI

NR Ghugre, V Ramanan, M Pop, Y Yang… - Magnetic …, 2011 - Wiley Online Library
Pathophysiological responses after acute myocardial infarction include edema, hemorrhage,
and microvascular obstruction along with cellular damage. The in vivo evolution of these …