Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …

Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are
renowned for their propensity to expel decondensed chromatin embedded with inflammatory …

Atherosclerosis is the main underlying pathology for many cardiovascular diseases (CVDs),
which are the leading cause of death globally and represent a serious health crisis …

Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) engages
the inflammasome in monocytes and macrophages and leads to the cytokine storm in …

Secondary immunodeficiency is reported in most patients with hematological malignancies
such as chronic lymphocytic leukemia and multiple myeloma. The aim of our review was to …

Diabetes mellitus is a metabolic disease largely due to lifestyle and nutritional imbalance,
resulting in insulin resistance, hyperglycemia and vascular complications. Diabetic kidney …

Immunothrombosis—immune-mediated activation of coagulation—is protective against
pathogens, but excessive immunothrombosis can result in pathological thrombosis and …

Neutrophils play a vital role in the formation of arterial, venous and cancer-related
thrombosis. Recent studies have shown that in a process known as NETosis, neutrophils …

Coagulopathy contributes to the majority of deaths and disabilities associated with traumatic
brain injury (TBI). Whether neutrophil extracellular traps (NETs) contribute to an abnormal …