In this contribution, we provide a comprehensive overview of C–H activation methods
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …

Direct C–H bond arylation of (hetero) arenes is a very convenient approach for the synthesis
of a wide variety of molecular targets, including compounds of pharmaceutical interest and π …

Imidazo [1, 2-a] pyridine has gained much interest in the field of drug development because
of its strong medicinal properties, therefore the discovery of novel methods for its synthesis …

Achieving site-selective, switchable C–H functionalizations of substrates that contain several
different types of reactive C–H bonds is an attractive objective to enable the generation of …

This review surveys recent developments (reported in the last fifteen years) in
organometallic‐chemistry‐based methods for the functionalization of imidazo [1, 2‐a] …

Ligand-free Pd (OAc) 2 was found to catalyze very efficiently the direct arylation of imidazo
[1, 2-a] pyridines at C3 under very low catalyst concentration. The reaction can be performed …

A series of sterically encumbered tetraarylimidazolium carbene Pd-PEPPSI complexes were
conveniently prepared and fully characterized. These sterically encumbered Pd-PEPPSI …

Direct arylation is a useful method for the preparation of (hetero) aryl–aryl systems by C–H
bond cleavage. This procedure has several advantages such as the reduction of cost, time …

On the basis of the strategy of develo** highly efficient protocol for Pd-catalyzed cross-
coupling reactions, a series of bulky bis (imino) acenaphthene (BIAN)-supported Pd-PEPPSI …

The palladium‐catalyzed functionalization of 5‐membered ring heteroaromatics, through a
C− H bonds activation, for access to arylated heteroaromatics represent a very attractive …