Broadening horizons: the role of ferroptosis in cancer

X Chen, R Kang, G Kroemer, D Tang - Nature reviews Clinical oncology, 2021 - nature.com
The discovery of regulated cell death processes has enabled advances in cancer treatment.
In the past decade, ferroptosis, an iron-dependent form of regulated cell death driven by …

The traditional medicine and modern medicine from natural products

H Yuan, Q Ma, L Ye, G Piao - Molecules, 2016 - mdpi.com
Natural products and traditional medicines are of great importance. Such forms of medicine
as traditional Chinese medicine, Ayurveda, Kampo, traditional Korean medicine, and Unani …

Artemisinin action and resistance in Plasmodium falciparum

L Tilley, J Straimer, NF Gnädig, SA Ralph… - Trends in …, 2016 - cell.com
The worldwide use of artemisinin-based combination therapies (ACTs) has contributed in
recent years to a substantial reduction in deaths resulting from Plasmodium falciparum …

Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies

Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - … and Targeted Therapy, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

C Dogovski, SC **e, G Burgio, J Bridgford, S Mok… - PLoS …, 2015 - journals.plos.org
Successful control of falciparum malaria depends greatly on treatment with artemisinin
combination therapies. Thus, reports that resistance to artemisinins (ARTs) has emerged …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - researchgate.net
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Anticancer activity of artemisinin and its derivatives

S Slezáková, J Ruda-Kucerova - Anticancer research, 2017 - ar.iiarjournals.org
Artemisinin is an extract from the plant Artemisia annua. With its semi-synthetic derivatives,
they form a group of well-known and efficacious antimalarial drugs. Recent studies have …

Phytochemical Analysis and Anti-Inflammatory Activity of Different Ethanolic Phyto-Extracts of Artemisia annua L.

G Abate, L Zhang, M Pucci, G Morbini, E Mac Sweeney… - Biomolecules, 2021 - mdpi.com
Artemisia annua L.(AA) has shown for many centuries important therapeutic virtues
associated with the presence of artemisinin (ART). The aim of this study was to identify and …

[HTML][HTML] Rearrangements of organic peroxides and related processes

IA Yaremenko, VA Vil, DV Demchuk… - Beilstein journal of …, 2016 - beilstein-journals.org
This review is the first to collate and summarize main data on named and unnamed
rearrangement reactions of peroxides. It should be noted, that in the chemistry of peroxides …

[HTML][HTML] Artemisinin, the magic drug discovered from traditional Chinese medicine

J Wang, C Xu, YK Wong, Y Li, F Liao, T Jiang, Y Tu - Engineering, 2019 - Elsevier
Artemisinin and its derivatives represent the most important and influential class of drugs in
the fight against malaria. Since the discovery of artemisinin in the early 1970s, the global …