The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …

The blood–brain barrier (BBB) protects the central nervous system (CNS) from unregulated
exposure to the blood and its contents. The BBB also controls the blood-to-brain and brain …

The age-associated decline of the neurological and cognitive functions becomes more and
more serious challenge for the developed countries with the increasing number of aged …

Among age-related diseases, cardiovascular and cerebrovascular diseases are major
causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age …

The blood–brain barrier (BBB) restricts free access of molecules between the blood and the
brain and is essential for regulating the neural microenvironment. Here, we describe how …

The aging of the central nervous system and the development of incapacitating neurological
diseases like Alzheimer's disease (AD) are generally associated with a wide range of …

Background Changes in the cerebral hemispheric white matter, detectable with increasing
frequency by modern neuroimaging methods, are associated with aging and conceivably …

The clinicopathologic entity of cerebral congophilic or amyloid angiopathy (CAA) has been
recognized since die early part of this century, though it has attained the'limelight'over the …

The retinal and cerebral microvasculatures share many morphological and physiological
properties. Assessment of the cerebral microvasculature requires highly specialized and …

The blood–brain barrier (BBB) is highly selective and acts as the interface between the
central nervous system and circulation. While the BBB is critical for maintaining brain …