The present paper considers recent progress in our understanding of the afferent/ascending
neural pathways and neural circuits of interoception. Of particular note is the extensive role …

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus
nerve stimulation (tVNS) across basic, translational and clinical research …

Three decades after its introduction as an adjuvant therapeutic option in the management of
selective drug-resistant epilepsy cases (DRE), vagus nerve stimulation (VNS) retains …

Electrical stimulation of the auricular vagus nerve (aVNS) is an emerging technology in the
field of bioelectronic medicine with applications in therapy. Modulation of the afferent vagus …

Interoceptive pathways may be manipulated at various levels to develop interventions to
improve symptoms in a range of disorders. Primarily through the lens of the respiratory …

It is well-recognized that, despite similar pain characteristics, some people with chronic pain
recover, whereas others do not. In this review, we discuss possible contributions and …

Vagus nerve stimulation (VNS) is an established form of neuromodulation with a long history
of promising applications. Earliest reports of VNS in the literature date to the late 1800's in …

Background Migraine is a highly prevalent primary headache disorder. Despite a high
burden of disease, key disease mechanisms are not entirely understood. Functional …

Given the high prevalence of individuals diagnosed with substance use disorder, along with
the elevated rate of relapse following treatment initiation, investigating novel approaches …

Background Brainstem-focused mechanisms supporting transcutaneous auricular VNS
(taVNS) effects are not well understood, particularly in humans. We employed ultrahigh field …