Sequencing pools of individuals—mining genome-wide polymorphism data without big funding

C Schlötterer, R Tobler, R Kofler, V Nolte - Nature Reviews Genetics, 2014 - nature.com
The analysis of polymorphism data is becoming increasingly important as a complementary
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs …

Genomics and the origin of species

O Seehausen, RK Butlin, I Keller, CE Wagner… - Nature Reviews …, 2014 - nature.com
Speciation is a fundamental evolutionary process, the knowledge of which is crucial for
understanding the origins of biodiversity. Genomic approaches are an increasingly …

Genetics on the Fly: A Primer on the Drosophila Model System

KG Hales, CA Korey, AM Larracuente, DM Roberts - Genetics, 2015 - academic.oup.com
Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …

Using next-generation sequencing to isolate mutant genes from forward genetic screens

K Schneeberger - Nature Reviews Genetics, 2014 - nature.com
The long-lasting success of forward genetic screens relies on the simple molecular basis of
the characterized phenotypes, which are typically caused by mutations in single genes …

Highly Contiguous Genome Assemblies of 15 Drosophila Species Generated Using Nanopore Sequencing

DE Miller, C Staber, J Zeitlinger… - G3: Genes, Genomes …, 2018 - academic.oup.com
The Drosophila genus is a unique group containing a wide range of species that occupy
diverse ecosystems. In addition to the most widely studied species, Drosophila …

Rapid evolutionary turnover underlies conserved lncRNA–genome interactions

JJ Quinn, QC Zhang, P Georgiev, IA Ilik… - Genes & …, 2016 - genesdev.cshlp.org
Many long noncoding RNAs (lncRNAs) can regulate chromatin states, but the evolutionary
origin and dynamics driving lncRNA–genome interactions are unclear. We adapted an …

Molecular population genetics

S Casillas, A Barbadilla - Genetics, 2017 - academic.oup.com
Molecular population genetics aims to explain genetic variation and molecular evolution
from population genetics principles. The field was born 50 years ago with the first measures …

Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila

CA Muirhead, DC Presgraves - Nature Ecology & Evolution, 2021 - nature.com
Sex chromosomes are susceptible to the evolution of selfish meiotic drive elements that bias
transmission and distort progeny sex ratios. Conflict between such sex-ratio drivers and the …

Population genomics from pool sequencing

L Ferretti, SE Ramos‐Onsins… - Molecular …, 2013 - Wiley Online Library
Next generation sequencing of pooled samples is an effective approach for studies of
variability and differentiation in populations. In this paper we provide a comprehensive set of …

[HTML][HTML] Non-random DNA fragmentation in next-generation sequencing

MS Poptsova, IA Il'Icheva, DY Nechipurenko… - Scientific reports, 2014 - nature.com
Abstract Next Generation Sequencing (NGS) technology is based on cutting DNA into small
fragments and their massive parallel sequencing. The multiple overlap** segments …