[HTML][HTML] Oxidative stress and age-related tumors

E Di Carlo, C Sorrentino - Antioxidants, 2024 - pmc.ncbi.nlm.nih.gov
Oxidative stress is the result of the imbalance between reactive oxygen and nitrogen species
(RONS), which are produced by several endogenous and exogenous processes, and …

Advances in targeting cancer epigenetics using CRISPR-dCas9 technology: a comprehensive review and future prospects

J Rajanathadurai, E Perumal, J Sindya - Functional & Integrative …, 2024 - Springer
Cancer, a complex and multifaceted group of diseases, continues to challenge the
boundaries of medical science and healthcare. Its relentless impact on global health, both in …

Liquid biopsies and exosomal ncRNA: Transforming pancreatic cancer diagnostics and therapeutics

AK Balaraman, E Moglad, M Afzal, MA Babu, K Goyal… - Clinica Chimica …, 2024 - Elsevier
Pancreatic cancer is a highly fatal malignancy due to poor early detection rate and
resistance to conventional therapies. This review examines the potential for liquid biopsy as …

[HTML][HTML] Advancements in pathology: Digital transformation, precision medicine, and beyond

S Ahuja, S Zaheer - Journal of Pathology Informatics, 2024 - Elsevier
Pathology, a cornerstone of medical diagnostics and research, is undergoing a revolutionary
transformation fueled by digital technology, molecular biology advancements, and big data …

The interplay of p16INK4a and non-coding RNAs: bridging cellular senescence, aging, and cancer

AK Balaraman, M Afzal, E Moglad, MA Babu, GP Priya… - Biogerontology, 2025 - Springer
Abstract p16INK4a is a crucial tumor suppressor and regulator of cellular senescence,
forming a molecular bridge between aging and cancer. Dysregulated p16INK4a expression …

Molecular simulations guided drugs repurposing to inhibit human GPx1 enzyme for cancer therapy

MW Iqbal, SZ Haider, MZ Nawaz, M Irfan… - Bioorganic …, 2025 - Elsevier
Overexpression of the antioxidant enzyme glutathione peroxidase-1 (GPx1) is associated
with different cancer types. Inhibitors of GPx1, including mercaptosuccinic acid and …

Machine-learning diagnostics of breast cancer using piRNA biomarkers

AR Zhao, VL Kouznetsova, S Kesari, IF Tsigelny - Biomarkers, 2025 - Taylor & Francis
Background and objectives Prior studies have shown that small non-coding RNAs
(sncRNAs) are associated with cancer occurrence or development. Recently, a newly …

Impact of cataranthine treatment on miRNA34 and miRNA29 levels in HepG2 cells and their association with the expression levels of Bcl-2 and Nrf2

N Heidari-Kalvani, F Mehdikhani, Y Mohammadi… - Molecular Biology …, 2025 - Springer
Introduction Cataranthine is an alkaloid used in the development of anti-cancer drugs. In this
study, the effect of cataranthine is assessed by measuring the levels of miR-34 and miRNA …

Tumor metastasis: mechanisms and prevention

S Paul - 2024 - gupea.ub.gu.se
Metastatic spread of tumor cells accounts for the majority of cancer-related deaths. We have
developed cancer vaccines based on the immunostimulatory adjuvant cholera toxin A1 …

[PDF][PDF] Apoptotic and Antiproliferative Effect of Thymoquinone on Ovarian Adenocarcinoma Cell Line Via The RAS/RAF Signaling Pathway

V Toprak, İ Özdemir, Ş Öztürk, YZ Kızıldemir, O Yanar… - 2024 - preprints.org
Aim: Ovarian cancer is one of the most frequently diagnosed cancers in women in the world.
Recognition of the differences between tumors in cancers and resistance to treatment in …