A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

Tetrahydrobiopterin (BH4) is an endogenous cofactor for some enzymatic conversions of
essential biomolecules, including nitric oxide, and monoamine neurotransmitters, and for the …

The global prevalence of obesity has been steadily increasing. Although pharmacotherapy
and bariatric surgeries can be useful adjuvants in the treatment of morbid obesity, they may …

Background Emerging research supports the idea that exercise positively affects
neurodevelopment. However, the mechanisms linking exercise with brain health are largely …

Evidence has shown that caffeine administration reduces pro-inflammatory biomarkers,
delaying fatigue and improving endurance performance. This study examined the effects of …

Improper glycemic carbohydrates (GCs) consumption can be a potential risk factor for
metabolic diseases such as obesity and diabetes, which may lead to cognitive impairment …

Beside its involvement in somatic dysfunctions, altered insulin signalling constitutes a risk
factor for the development of mental disorders like Alzheimer's disease and obsessive …

Heat stress (HS) induces various pathophysiological responses in the brain, encompassing
neuroinflammation and cognitive impairments. Although taurine has been reported to …

Benefits of exercise have been documented for many diseases with a chronic progression,
including obesity, diabetes mellitus, cardiovascular diseases, neurodegenerative diseases …

Obesity and metabolic disorders are increasing worldwide and are associated with brain
atrophy and dysfunction, which are risk factors for late-onset dementia and Alzheimer's …