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Preparing the ground for tissue regeneration: from mechanism to therapy
Chronic diseases confer tissue and organ damage that reduce quality of life and are largely
refractory to therapy. Although stem cells hold promise for treating degenerative diseases …
refractory to therapy. Although stem cells hold promise for treating degenerative diseases …
Lying low but ready for action: the quiescent muscle satellite cell
D Montarras, A L'honoré, M Buckingham - The FEBS journal, 2013 - Wiley Online Library
The muscle satellite cell is essential for skeletal muscle regeneration. It is located on the
muscle fibre, under the basal lamina as a quiescent cell, which becomes activated after …
muscle fibre, under the basal lamina as a quiescent cell, which becomes activated after …
Dynamic ligand discrimination in the notch signaling pathway
The Notch signaling pathway comprises multiple ligands that are used in distinct biological
contexts. In principle, different ligands could activate distinct target programs in signal …
contexts. In principle, different ligands could activate distinct target programs in signal …
Type-2 pericytes participate in normal and tumoral angiogenesis
Tissue growth and function depend on vascularization, and vascular insufficiency or excess
exacerbates many human diseases. Identification of the biological processes involved in …
exacerbates many human diseases. Identification of the biological processes involved in …
Exosomal miR-9 inhibits angiogenesis by targeting MDK and regulating PDK/AKT pathway in nasopharyngeal carcinoma
J Lu, QH Liu, F Wang, JJ Tan, YQ Deng… - Journal of Experimental …, 2018 - Springer
Background Exosomes are small vesicles containing a wide range of functional proteins,
mRNA and miRNA. Exosomal miRNAs from cancer cells play crucial roles in mediating cell …
mRNA and miRNA. Exosomal miRNAs from cancer cells play crucial roles in mediating cell …
Live imaging of axolotl digit regeneration reveals spatiotemporal choreography of diverse connective tissue progenitor pools
Connective tissues—skeleton, dermis, pericytes, fascia—are a key cell source for
regenerating the patterned skeleton during axolotl appendage regeneration. This complexity …
regenerating the patterned skeleton during axolotl appendage regeneration. This complexity …
Satellite cells: the architects of skeletal muscle
The outstanding regenerative capacity of skeletal muscle is attributed to the resident muscle
stem cell termed satellite cell. Satellite cells are essential for skeletal muscle regeneration as …
stem cell termed satellite cell. Satellite cells are essential for skeletal muscle regeneration as …
The panniculus carnosus muscle: an evolutionary enigma at the intersection of distinct research fields
The panniculus carnosus is a thin striated muscular layer intimately attached to the skin and
fascia of most mammals, where it provides skin twitching and contraction functions. In …
fascia of most mammals, where it provides skin twitching and contraction functions. In …
Skeletal and cardiac muscle pericytes: Functions and therapeutic potential
Pericytes are periendothelial mesenchymal cells residing within the microvasculature.
Skeletal muscle and cardiac pericytes are now recognized to fulfill an increasing number of …
Skeletal muscle and cardiac pericytes are now recognized to fulfill an increasing number of …
Single‐cell RNA‐sequencing provides insight into skeletal muscle evolution during the selection of muscle characteristics
Skeletal muscle comprises a large, heterogeneous assortment of cell populations that
interact to maintain muscle homeostasis, but little is known about the mechanism that …
interact to maintain muscle homeostasis, but little is known about the mechanism that …