Sleep is highly conserved across evolution, suggesting vital biological functions that are yet
to be fully understood. Animals and humans experiencing partial sleep restriction usually …

Until recently, the association of chronic insomnia with significant medical morbidity was not
established and its diagnosis was based solely on subjective complaints. We present …

Sleep and circadian rhythms modulate or control daily physiological patterns with
importance for normal metabolic health. Sleep deficiencies associated with insufficient sleep …

All organisms must maintain a complex dynamic equilibrium, or homeostasis, which is
constantly challenged by internal or external adverse forces termed stressors. Stress occurs …

As obesity and diabetes reach epidemic proportions in the developed world, the role of
insulin resistance and its consequences are gaining prominence. Understanding the role of …

Background: Of all the psychiatric disorders associated with insomnia, depression is the
most common. It has been estimated that 90% of patients with depression complain about …

Total sleep restriction in humans is associated with increased daytime sleepiness,
decreased performance, and hormonal/metabolic disturbances. The effects of mild chronic …

Frequently disrupted and restricted sleep is a common problem for many people in our
modern around-the-clock society. In this context, it is an important question how sleep loss …

BACKGROUND: Electrolyte disorders have been studied mainly in hospitalized patients,
whereas data in the general population are limited. The aim of this study was to determine …

Although insomnia is, by far, the most commonly encountered sleep disorder in medical
practice, our knowledge in regard to its neurobiology and medical significance is limited …