1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Described herein is an organocatalytic enantioselective desymmetrizing cycloisomerization
of arylsulfonyl‐protected ynamide cyclohexanones, representing the first metal‐free …

Herein we describe the use of synergistic Pd and Cu catalysis for stereodivergent coupling
reactions between 1, 3-dienes and aldimine esters. By using different enantiomers of the two …

Selective transformation of alkyne triple bonds to double bonds serves as an efficient
platform to construct substituted alkenes. While significant advances have been made in its …

Herein, we describe the convergent enantioselective total synthesis of himalensine A in 18
steps, enabled by a highly enantio-and diastereoselective construction of the morphan core …

A reagent‐controlled stereodivergent carbocyclisation of aryl aldimine‐derived,
photocatalytically generated, α‐amino radicals possessing adjacent conjugated alkenes …

Direct functionalization of carbonyl β C–H bonds without using directing groups has not
been a trivial task, and it is even more challenging to realize the corresponding atom …

An efficient desymmetrization of γ-quaternary carbon-containing cyclohexanones using
readily available Pd/(S)-t BuPhox and benzylamine as dual catalysts is reported. We …

The combination of a Pd (0) complex with benzoic acid in the presence of D2O enables the
synthesis of valuable families of highly deuterated organics through elaborate sequential …

Understanding the nature of a transition-metal-catalyzed process, including catalyst
evolution and the real active species, is rather challenging yet of great importance for the …