Potential antiviral action of alkaloids
Viral infections and outbreaks have become a major concern and are one of the main
causes of morbidity and mortality worldwide. The development of successful antiviral …
causes of morbidity and mortality worldwide. The development of successful antiviral …
Mastering the Gram-negative bacterial barrier–Chemical approaches to increase bacterial bioavailability of antibiotics
HK Ropponen, R Richter, AKH Hirsch… - Advanced Drug Delivery …, 2021 - Elsevier
To win the battle against resistant, pathogenic bacteria, novel classes of anti-infectives and
targets are urgently needed. Bacterial uptake, distribution, metabolic and efflux pathways of …
targets are urgently needed. Bacterial uptake, distribution, metabolic and efflux pathways of …
Synthesis and intensive characterization for novel Zn (II), Pd (II), Cr (III) and VO (II)-Schiff base complexes; DNA-interaction, DFT, drug-likeness and molecular docking …
A novel bioactive series was synthesized from Zn (II), Pd (II), Cr (III) and VO (II) ions with a
new Schiff base derivative (HNP)[HNP= 1-(Pyrimidin-2-yliminomethyl)-naphthalen-2-ol]. The …
new Schiff base derivative (HNP)[HNP= 1-(Pyrimidin-2-yliminomethyl)-naphthalen-2-ol]. The …
A robust in vitro Anticancer, Antioxidant and Antimicrobial Agents Based on New Metal‐Azomethine Chelates Incorporating Ag(I), Pd (II) and VO (II) Cations: Probing …
AM Abu‐Dief, LH Abdel‐Rahman… - Applied …, 2020 - Wiley Online Library
A novel azomethine ligand (HNAP)[HNAP= 1‐(Pyridin‐3‐yliminomethyl)‐naphthalen‐2‐ol]
and its Ag (I), Pd (II) and VO (II) chelates have been synthesized and structurally inspected …
and its Ag (I), Pd (II) and VO (II) chelates have been synthesized and structurally inspected …
Structural inspection for novel Pd (II), VO (II), Zn (II) and Cr (III)-azomethine metal chelates: DNA interaction, biological screening and theoretical treatments
An alternative sequence of bioactive series, using novel Schiff base derivative (1-Quinolin-8-
yliminomethyl-naphthalen-2-ol), was produced (HNQ). Elements analysis, molar …
yliminomethyl-naphthalen-2-ol), was produced (HNQ). Elements analysis, molar …
Novel 1, 3, 5-triazine-based pyrazole derivatives as potential antitumor agents and EFGR kinase inhibitors: Synthesis, cytotoxicity, DNA binding, molecular docking …
We herein report the design and synthesis of new 1, 3, 5-triazine-based pyrazole derivatives
(5a–i) with anticancer activity targeting the epidermal growth factor (EGFR) tyrosine kinase …
(5a–i) with anticancer activity targeting the epidermal growth factor (EGFR) tyrosine kinase …
Optimization for synthesized quinoline-based Cr3+, VO2+, Zn2+ and Pd2+ complexes: DNA interaction, biological assay and in-silico treatments for verification
HA Al-Abdulkarim, RM El-khatib, FS Aljohani… - Journal of Molecular …, 2021 - Elsevier
A novel momonuclear metal chelates were derived from Zn (II), Pd (II), VO (II) and Cr (III) ions
with azomethine (BSQ)[BSQ= 4-Bromo-2-(quinolin-8-yliminomethyl)-phenol] ligand. The …
with azomethine (BSQ)[BSQ= 4-Bromo-2-(quinolin-8-yliminomethyl)-phenol] ligand. The …
Some new Ag (I), VO (II) and Pd (II) chelates incorporating tridentate imine ligand: Design, synthesis, structure elucidation, density functional theory calculations for …
LH Abdel‐Rahman, AM Abu‐Dief… - Applied …, 2019 - Wiley Online Library
Some new complexes derived from VO (II), Ag (I) and Pd (II) metal ions and HNA imine
ligand (L), ie (2‐((6‐allylidene‐2‐hydroxycyclohexa‐1, 3‐dienylmethylene) amino) benzoic …
ligand (L), ie (2‐((6‐allylidene‐2‐hydroxycyclohexa‐1, 3‐dienylmethylene) amino) benzoic …
DNA damaging agents and DNA repair: From carcinogenesis to cancer therapy
Cancer genome instability arises from diverse defects in DNA-repair machinery, which make
cancer cells more susceptible to DNA targeting agents. The interrelation between DNA …
cancer cells more susceptible to DNA targeting agents. The interrelation between DNA …
Supramolecular Loading of DNA Hydrogels with Dye–Drug Conjugates for Real‐Time Photoacoustic Monitoring of Chemotherapy
A longstanding problem with conventional cancer therapy is the nonspecific distribution of
chemotherapeutics. Monitoring drug release in vivo via noninvasive bioimaging can thus …
chemotherapeutics. Monitoring drug release in vivo via noninvasive bioimaging can thus …