The roles of nucleoid-associated proteins and topoisomerases in chromosome structure, strand segregation, and the generation of phenotypic heterogeneity in …

V Norris, C Kayser, G Muskhelishvili… - FEMS Microbiology …, 2023 - academic.oup.com
How to adapt to a changing environment is a fundamental, recurrent problem confronting
cells. One solution is for cells to organize their constituents into a limited number of spatially …

Bacterial lipid biophysics and membrane organization

LMY Mitchison-Field, BJ Belin - Current Opinion in Microbiology, 2023 - Elsevier
The formation of lateral microdomains is emerging as a central organizing principle in
bacterial membranes. These microdomains are targets of antibiotic development and have …

[HTML][HTML] SRRF: Universal live-cell super-resolution microscopy

S Culley, KL Tosheva, PM Pereira… - The international journal of …, 2018 - Elsevier
Super-resolution microscopy techniques break the diffraction limit of conventional optical
microscopy to achieve resolutions approaching tens of nanometres. The major advantage of …

TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation

P Stolz, AS Mantero, A Tvardovskiy, E Ugur… - Nucleic Acids …, 2022 - academic.oup.com
Abstract DNA methylation (5-methylcytosine (5mC)) is critical for genome stability and
transcriptional regulation in mammals. The discovery that ten-eleven translocation (TET) …

The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors

X Zheng, G Marsman, KA Lacey, JR Chapman… - Nature …, 2021 - nature.com
Staphylococcus aureus bi-component pore-forming leukocidins are secreted toxins that
directly target and lyse immune cells. Intriguingly, one of the leukocidins, Leukocidin AB …

Assessing membrane fluidity and visualizing fluid membrane domains in bacteria using fluorescent membrane dyes

M Wenzel, NOE Vischer, H Strahl, LW Hamoen - Bio-protocol, 2018 - bio-protocol.org
Membrane fluidity is a key parameter of bacterial membranes that undergoes quick
adaptation in response to environmental challenges and has recently emerged as an …

Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals

CB Mulholland, A Nishiyama, J Ryan… - Nature …, 2020 - nature.com
Genome-wide DNA demethylation is a unique feature of mammalian development and
naïve pluripotent stem cells. Here, we describe a recently evolved pathway in which global …

Resonance energy transfer-based biosensors for point-of-need diagnosis—progress and perspectives

F Weihs, A Anderson, S Trowell, K Caron - Sensors, 2021 - mdpi.com
The demand for point-of-need (PON) diagnostics for clinical and other applications is
continuing to grow. Much of this demand is currently serviced by biosensors, which combine …

Organization of peptidoglycan synthesis in nodes and separate rings at different stages of cell division of Streptococcus pneumoniae

AJ Perez, MJ Boersma, KE Bruce… - Molecular …, 2021 - Wiley Online Library
Bacterial peptidoglycan (PG) synthesis requires strict spatiotemporal organization to
reproduce specific cell shapes. In ovoid‐shaped Streptococcus pneumoniae (Spn), septal …

Super‐Resolution Near‐Infrared Fluorescence Microscopy of Single‐Walled Carbon Nanotubes Using Deep Learning

B Kagan, A Hendler-Neumark, V Wulf… - Advanced Photonics …, 2022 - Wiley Online Library
Single‐walled carbon nanotubes (SWCNTs) have unique optical and physical properties,
with numerous biomedical imaging and sensing applications, owing to their near‐infrared …