The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

The extracellular matrix (ECM) of natural cells typically exhibits dynamic mechanical
properties (viscoelasticity and dynamic stiffness). The viscoelasticity and dynamic stiffness of …

Osteoarthritis (OA) is a prevalent disease, characterized by subchondral fractures in its initial
stages, which has no precise and specific treatment now. Here, a novel multifunctional …

The treatment of osteochondral defects (OCD) remains challenging. Among currently
available surgical treatments for OCDs, scaffold-based treatments are promising to …

Over centuries, several advances have been made in osteochondral (OC) tissue
engineering to regenerate more biomimetic tissue. As an essential component of tissue …

To establish a histopathological scoring system for changes in subchondral bone in murine
models of knee osteoarthritis (OA), three key parameters, subchondral bone plate (Subcho …

Osteoarthritis (OA) is a chronic, progressive, severely debilitating, and multifactorial joint
disease that is recognized as the most common type of arthritis. During the last decade, it …

Osteoarthritis (OA) is a degenerative bone disease associated with aging. The rising global
aging population has led to a surge in OA cases, thereby imposing a significant …

Regenerative engineering holds the potential to treat clinically pervasive osteochondral
defects (OCDs). In a synthetic materials-guided approach, the scaffold's chemical and …

Cryogels are matrices that are formed in moderately frozen solutions of monomeric or
polymeric precursors. They have the advantages of interconnected macropores, structural …