Tackling the emerging threat of antifungal resistance to human health

MC Fisher, A Alastruey-Izquierdo, J Berman… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Killing softly: a roadmap of Botrytis cinerea pathogenicity

K Bi, Y Liang, T Mengiste, A Sharon - Trends in plant science, 2023 - cell.com
Botrytis cinerea, a widespread plant pathogen with a necrotrophic lifestyle, causes gray
mold disease in many crops. Massive secretion of enzymes and toxins was long considered …

Plant small RNAs: their biogenesis, regulatory roles, and functions

J Zhan, BC Meyers - Annual Review of Plant Biology, 2023 - annualreviews.org
Plant cells accumulate small RNA molecules that regulate plant development, genome
stability, and environmental responses. These small RNAs fall into three major classes …

Roles of RNA silencing in viral and non-viral plant immunity and in the crosstalk between disease resistance systems

S Lopez-Gomollon, DC Baulcombe - Nature Reviews Molecular Cell …, 2022 - nature.com
RNA silencing is a well-established antiviral immunity system in plants, in which small RNAs
guide Argonaute proteins to targets in viral RNA or DNA, resulting in virus repression. Virus …

Address the growing urgency of fungal disease in crops

E Stukenbrock, S Gurr - Nature, 2023 - nature.com
Address the growing urgency of fungal disease in crops Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Foliar application of clay-delivered RNA interference for whitefly control

RG Jain, SJ Fletcher, N Manzie, KE Robinson, P Li… - Nature Plants, 2022 - nature.com
Whitefly (Bemisia tabaci) is a phloem-feeding global agricultural pest belonging to the order
Hemiptera. Foliar application of double-stranded RNA (dsRNA) represents an attractive …

[HTML][HTML] Plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection

S Wang, B He, H Wu, Q Cai, O Ramírez-Sánchez… - Cell host & …, 2024 - cell.com
Cross-kingdom small RNA trafficking between hosts and microbes modulates gene
expression in the interacting partners during infection. However, whether other RNAs are …

RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles

B He, Q Cai, L Qiao, CY Huang, S Wang, W Miao, T Ha… - Nature plants, 2021 - nature.com
Plants use extracellular vesicles (EVs) to transport small RNAs (sRNAs) into their fungal
pathogens and silence fungal virulence-related genes through a phenomenon called 'cross …

Fungal small RNAs ride in extracellular vesicles to enter plant cells through clathrin-mediated endocytosis

B He, H Wang, G Liu, A Chen, A Calvo, Q Cai… - Nature …, 2023 - nature.com
Small RNAs (sRNAs) of the fungal pathogen Botrytis cinerea can enter plant cells and hijack
host Argonaute protein 1 (AGO1) to silence host immunity genes. However, the mechanism …

Threats posed by the fungal kingdom to humans, wildlife, and agriculture

MC Fisher, SJ Gurr, CA Cuomo, DS Blehert, H **… - MBio, 2020 - journals.asm.org
The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with
respect to its profound impact on global health, biodiversity, ecology, agriculture …