Advances in PET imaging of cancer

J Schwenck, D Sonanini, JM Cotton… - Nature Reviews …, 2023 - nature.com
Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

The many facets of therapy resistance and tumor recurrence in glioblastoma

A Goenka, D Tiek, X Song, T Huang, B Hu, SY Cheng - Cells, 2021 - mdpi.com
Glioblastoma (GBM) is the most lethal type of primary brain cancer. Standard care using
chemo-and radio-therapy modestly increases the overall survival of patients; however …

All‐in‐one biomimetic nanoplatform based on hollow polydopamine nanoparticles for synergistically enhanced radiotherapy of colon cancer

L Gong, Y Zhang, J Zhao, Y Zhang, K Tu, L Jiao, Q Xu… - Small, 2022 - Wiley Online Library
Even though radiotherapy is the most important therapeutic strategy for colon cancer
treatment, there is an enormous demand to improve radiosensitivity in solid tumor …

Radioresistance in Glioblastoma and the Development of Radiosensitizers

MY Ali, CR Oliva, ASM Noman, BG Allen, PC Goswami… - Cancers, 2020 - mdpi.com
Simple Summary Numerous mechanisms of glioblastoma (GBM) radioresistance have been
identified but have not yet resulted in development of effective radiosensitizer that can …

Opportunities for improving brain cancer treatment outcomes through imaging-based mathematical modeling of the delivery of radiotherapy and immunotherapy

DA Hormuth II, M Farhat, C Christenson, B Curl… - Advanced drug delivery …, 2022 - Elsevier
Immunotherapy has become a fourth pillar in the treatment of brain tumors and, when
combined with radiation therapy, may improve patient outcomes and reduce the …

GFAP splice variants fine-tune glioma cell invasion and tumour dynamics by modulating migration persistence

R Uceda-Castro, JV van Asperen, C Vennin… - Scientific Reports, 2022 - nature.com
Glioma is the most common form of malignant primary brain tumours in adults. Their highly
invasive nature makes the disease incurable to date, emphasizing the importance of better …

Targeting drug resistance in glioblastoma

JH Sherman, A Bobak, T Arsiwala… - International …, 2024 - spandidos-publications.com
Glioblastoma (GBM) is the most common malignancy of the central nervous system in adults.
The current standard of care includes surgery, radiation therapy, temozolomide; and tumor …

[HTML][HTML] The hallmarks of cancer as ecologically driven phenotypes

JA Somarelli - Frontiers in ecology and evolution, 2021 - frontiersin.org
Ecological fitness is the ability of individuals in a population to survive and reproduce.
Individuals with increased fitness are better equipped to withstand the selective pressures of …

The role of hypoxia and SRC tyrosine kinase in glioblastoma invasiveness and radioresistance

F Torrisi, N Vicario, FM Spitale, FP Cammarata… - Cancers, 2020 - mdpi.com
Simple Summary The biological pathways underlying glioblastoma malignancy and
radioresistance are still unclear. In this review, we describe the role of the hypoxic …

A versatile nanoplatform carrying cascade Pt nanozymes remodeling tumor microenvironment for amplified sonodynamic/chemo therapy of thyroid cancer

D Wang, W Ma, Y Zhang, Y Wang, L Sun, J Jiang… - Biomaterials, 2025 - Elsevier
Thyroid cancer is increasing globally, with anaplastic thyroid carcinoma (ATC) being the
most aggressive type and having a poor prognosis. Current clinical treatments for thyroid …