[HTML][HTML] One size does not fit all: methodological considerations for brain-based predictive modeling in psychiatry

E Dhamala, BTT Yeo, AJ Holmes - Biological Psychiatry, 2023 - Elsevier
Psychiatric illnesses are heterogeneous in nature. No illness manifests in the same way
across individuals, and no two patients with a shared diagnosis exhibit identical symptom …

Brain–phenotype models fail for individuals who defy sample stereotypes

AS Greene, X Shen, S Noble, C Horien, CA Hahn… - Nature, 2022 - nature.com
Individual differences in brain functional organization track a range of traits, symptoms and
behaviours,,,,,,,,,,–. So far, work modelling linear brain–phenotype relationships has …

Data leakage inflates prediction performance in connectome-based machine learning models

M Rosenblatt, L Tejavibulya, R Jiang, S Noble… - Nature …, 2024 - nature.com
Predictive modeling is a central technique in neuroimaging to identify brain-behavior
relationships and test their generalizability to unseen data. However, data leakage …

[HTML][HTML] COVID‐19 vicarious traumatization links functional connectome to general distress

X Suo, C Zuo, H Lan, N Pan, X Zhang, GJ Kemp… - Neuroimage, 2022 - Elsevier
As characterized by repeated exposure of others' trauma, vicarious traumatization is a
common negative psychological reaction during the COVID-19 pandemic and plays a …

Modeling spatio-temporal patterns of holistic functional brain networks via multi-head guided attention graph neural networks (Multi-Head GAGNNs)

J Yan, Y Chen, Z **ao, S Zhang, M Jiang, T Wang… - Medical Image …, 2022 - Elsevier
Mounting evidence has demonstrated that complex brain function processes are realized by
the interaction of holistic functional brain networks which are spatially distributed across …

A cognitive neurogenetic approach to uncovering the structure of executive functions

J Feng, L Zhang, C Chen, J Sheng, Z Ye, K Feng… - Nature …, 2022 - nature.com
One central mission of cognitive neuroscience is to understand the ontology of complex
cognitive functions. We addressed this question with a cognitive neurogenetic approach …

Sex differences in default mode network connectivity in healthy aging adults

B Ficek-Tani, C Horien, S Ju, W Xu, N Li… - Cerebral …, 2023 - academic.oup.com
Women show an increased lifetime risk of Alzheimer's disease (AD) compared with men.
Characteristic brain connectivity changes, particularly within the default mode network …

Activity flow underlying abnormalities in brain activations and cognition in schizophrenia

LJ Hearne, RD Mill, BP Keane, G Repovš… - Science …, 2021 - science.org
Cognitive dysfunction is a core feature of many brain disorders, including schizophrenia
(SZ), and has been linked to aberrant brain activations. However, it is unclear how these …