Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium

B Shen, GS Kochhar, DT Rubin, SV Kane… - The Lancet …, 2022 - thelancet.com
Pouchitis, Crohn's disease of the pouch, cuffitis, polyps, and extraintestinal manifestations of
inflammatory bowel disease are common inflammatory disorders of the ileal pouch. Acute …

AGA clinical practice guideline on the management of pouchitis and inflammatory pouch disorders

EL Barnes, M Agrawal, G Syal, AN Ananthakrishnan… - Gastroenterology, 2024 - Elsevier
Background & Aims Pouchitis is the most common complication after restorative
proctocolectomy with ileal pouch–anal anastomosis for ulcerative colitis. This American …

Long-term bowel function and fate of the ileal pouch after restorative proctocolectomy in patients with Crohn's disease: a systematic review with meta-analysis and …

G Pellino, D Vinci, G Signoriello… - Journal of Crohn's …, 2020 - academic.oup.com
Abstract Background and Aims Debate exists on whether ileal pouch anal anastomosis
[IPAA] can be safely offered to patients diagnosed with Crohn's disease [CD]. Our aim was to …

Outcome of biological therapies in chronic antibiotic-refractory pouchitis: a retrospective single-centre experience

B Verstockt, C Claeys, G De Hertogh… - United European …, 2019 - journals.sagepub.com
Background In limited retrospective series, infliximab, adalimumab and vedolizumab have
demonstrated efficacy in chronic antibiotic-refractory pouchitis. Here, we report single-centre …

Controversies in Crohn's disease before and after pouch surgery

SR Shaffer, CN Bernstein - Diseases of the Colon & Rectum, 2022 - journals.lww.com
BACKGROUND: IPAA is rarely performed in patients with a known diagnosis of Crohn's
disease, although it may be done in highly selected patients with an absence of perianal …

Vedolizumab for treatment of chronic refractory pouchitis: a systematic review with pool analysis

DG Ribaldone, R Pellicano, GM Saracco… - Revista Espanola De …, 2020 - iris.unito.it
about 1%-2% of patients with chronic refractory pouchitis, in the context of ulcerative colitis,
end up with a permanent ileostomy. The aim of this systematic review was to collect all …

Continent ileostomy as an alternative to end ileostomy

X Wu, H Ke, RP Kiran, B Shen… - … Research and Practice, 2020 - Wiley Online Library
Continent ileostomy (CI) was once a prevalent surgical technique for patients who required
total proctocolectomy but then gave way to ileal pouch‐anal anastomosis (IPAA) after 1980 …

Endoscopy in Postoperative Patients with Crohn's Disease or Ulcerative Colitis. Does It Translate to Better Outcomes?

A Bhattacharya, B Shen… - Gastrointestinal …, 2019 - giendo.theclinics.com
Both Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory disorders of
the gastrointestinal system. Although CD can involve the mouth to the anus, UC is limited …

The pouch behaving badly: management of morbidity after ileal pouch–anal anastomosis

M Deputy, J Segal, L Reza, G Worley… - Colorectal …, 2021 - Wiley Online Library
Aim Ileal pouch–anal anastomosis (IPAA), or a 'pouch', allows restoration of intestinal
continuity after proctocolectomy for ulcerative colitis or familial adenomatous polyposis. Most …

Comprehensive systematic review and pooled analysis of real‐world studies evaluating immunomodulator and biologic therapies for chronic pouchitis treatment

E Khoo, A Lee, T Neeman, YK An, J Begun - JGH Open, 2023 - Wiley Online Library
Abstract Background and Aim Pouchitis is a common complication after restorative ileal
pouch–anal anastomosis following proctocolectomy for ulcerative colitis. Antibiotic …