Peptidoglycan NlpC/P60 peptidases in bacterial physiology and host interactions
The bacterial cell wall is composed of a highly crosslinked matrix of glycopeptide polymers
known as peptidoglycan that dictates bacterial cell morphology and protects against …
known as peptidoglycan that dictates bacterial cell morphology and protects against …
Targeting the Achilles' heel of bacteria: different mechanisms to break down the peptidoglycan cell wall during bacterial warfare
S Sibinelli-Sousa, JT Hespanhol… - Journal of …, 2021 - Am Soc Microbiol
Bacteria commonly live in dense polymicrobial communities and compete for scarce
resources. Consequently, they employ a diverse array of mechanisms to harm, inhibit, and …
resources. Consequently, they employ a diverse array of mechanisms to harm, inhibit, and …
VxrB influences antagonism within biofilms by controlling competition through extracellular matrix production and type 6 secretion
The human pathogen Vibrio cholerae grows as biofilms, communities of cells encased in an
extracellular matrix. When growing in biofilms, cells compete for resources and space. One …
extracellular matrix. When growing in biofilms, cells compete for resources and space. One …
The type VI secretion system of the emerging pathogen Stenotrophomonas maltophilia complex has antibacterial properties
Antagonistic behaviors between bacterial cells can have profound effects on microbial
populations and disease outcomes. Polymicrobial interactions may be mediated by contact …
populations and disease outcomes. Polymicrobial interactions may be mediated by contact …
Multiple T6SSs, mobile auxiliary modules, and effectors revealed in a systematic analysis of the Vibrio parahaemolyticus pan-genome
Type VI secretion systems (T6SSs) play a major role in interbacterial competition and in
bacterial interactions with eukaryotic cells. The distribution of T6SSs and the effectors they …
bacterial interactions with eukaryotic cells. The distribution of T6SSs and the effectors they …
A putative lipoprotein mediates cell-cell contact for type VI secretion system-dependent killing of specific competitors
Interbacterial competition is prevalent in host-associated microbiota, where it can shape
community structure and function, impacting host health in both positive and negative ways …
community structure and function, impacting host health in both positive and negative ways …
Type 1 fimbriae-mediated collective protection against type 6 secretion system attacks
Bacterial competition may rely on secretion systems such as the type 6 secretion system
(T6SS), which punctures and releases toxic molecules into neighboring cells. To subsist …
(T6SS), which punctures and releases toxic molecules into neighboring cells. To subsist …
Engineered type six secretion systems deliver active exogenous effectors and cre recombinase
Genetic editing has revolutionized biotechnology, but delivery of endonuclease genes as
DNA can lead to aberrant integration or overexpression, leading to off-target effects. Here …
DNA can lead to aberrant integration or overexpression, leading to off-target effects. Here …
Antibacterial potential of Stenotrophomonas maltophilia complex cystic fibrosis isolates
Over 160,000 people worldwide suffer from cystic fibrosis (CF), a genetic condition that
causes mucus to accumulate in internal organs. Lung decline is a significant health burden …
causes mucus to accumulate in internal organs. Lung decline is a significant health burden …
Characterization of lysozyme-like effector TseP reveals the dependence of type VI secretion system (T6SS) secretion on effectors in Aeromonas dhakensis strain SSU
X Liang, TT Pei, ZH Wang, W **ong… - Applied and …, 2021 - Am Soc Microbiol
The type VI secretion system (T6SS) is a widespread weapon employed by Gram-negative
bacteria for interspecies interaction in complex communities. Analogous to a contractile …
bacteria for interspecies interaction in complex communities. Analogous to a contractile …