Develo** biomedical engineering technologies for reproductive medicine

Y Zhu, B Kong, R Liu, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …

Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics

C Honrado, P Bisegna, NS Swami, F Caselli - Lab on a Chip, 2021 - pubs.rsc.org
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …

Recent progress in high-throughput droplet screening and sorting for bioanalysis

G Sun, L Qu, F Azi, Y Liu, J Li, X Lv, G Du… - Biosensors and …, 2023 - Elsevier
Owing to its ability to isolate single cells and perform high-throughput sorting, droplet sorting
has been widely applied in several research fields. Compared with flow cytometry, droplet …

Microfluidics for sperm analysis and selection

R Nosrati, PJ Graham, B Zhang, J Riordon… - Nature Reviews …, 2017 - nature.com
Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …

Deciphering impedance cytometry signals with neural networks

F Caselli, R Reale, A De Ninno, D Spencer, H Morgan… - Lab on a Chip, 2022 - pubs.rsc.org
Microfluidic impedance cytometry is a label-free technique for high-throughput single-cell
analysis. Multi-frequency impedance measurements provide data that allows full …

Sperm selection in assisted reproduction: A review of established methods and cutting-edge possibilities

G Marzano, MS Chiriacò, E Primiceri… - Biotechnology …, 2020 - Elsevier
Male infertility often involves idiopathic or unknown causes, leading to an increasing
demand for assisted reproduction technologies (ART). Conventional sperm sorting …

A microfluidic device integrating impedance flow cytometry and electric impedance spectroscopy for high-efficiency single-cell electrical property measurement

Y Feng, L Huang, P Zhao, F Liang, W Wang - Analytical chemistry, 2019 - ACS Publications
Single-cell impedance measurement is a label-free, noninvasive method for characterizing
the electrical properties of single cells. At present, though widely used for impedance …

Sperm selection methods in the 21st century

DA Vaughan, D Sakkas - Biology of reproduction, 2019 - academic.oup.com
Natural sperm selection in humans is a rigorous process resulting in the highest quality
sperm reaching, and having an opportunity to fertilize, the oocyte. Relative to other …

[HTML][HTML] Microfluidic—based sperm sorting & analysis for treatment of male infertility

R Samuel, H Feng, A Jafek, D Despain… - Translational …, 2018 - ncbi.nlm.nih.gov
Microfluidics technology has emerged as an enabling technology for different fields of
medicine and life sciences. One such field is male infertility where microfluidic technologies …

Microfluidics for cryopreservation

G Zhao, J Fu - Biotechnology advances, 2017 - Elsevier
Cryopreservation has utility in clinical and scientific research but implementation is highly
complex and includes labor-intensive cell-specific protocols for the addition/removal of …