Cancer immunotherapy with γδ T cells: many paths ahead of us
D Kabelitz, R Serrano, L Kouakanou, C Peters… - Cellular & molecular …, 2020 - nature.com
Abstract γδ T cells play uniquely important roles in stress surveillance and immunity for
infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells …
infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells …
[HTML][HTML] Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment
Natural compounds are widely used to prevent and treat various diseases due to their
antioxidant and anti-inflammatory effects. As a kind of promising natural compound, plant …
antioxidant and anti-inflammatory effects. As a kind of promising natural compound, plant …
GSCA: an integrated platform for gene set cancer analysis at genomic, pharmacogenomic and immunogenomic levels
Cancer initiation and progression are likely caused by the dysregulation of biological
pathways. Gene set analysis (GSA) could improve the signal-to-noise ratio and identify …
pathways. Gene set analysis (GSA) could improve the signal-to-noise ratio and identify …
First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial
Although patients with microsatellite instable metastatic colorectal cancer (CRC) benefit from
immune checkpoint blockade, chemotherapy with targeted therapies remains the only …
immune checkpoint blockade, chemotherapy with targeted therapies remains the only …
T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing
H Chi, S Zhao, J Yang, X Gao, G Peng… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC), the third most prevalent cause of cancer-
related death, is a frequent primary liver cancer with a high rate of morbidity and mortality. T …
related death, is a frequent primary liver cancer with a high rate of morbidity and mortality. T …
Crosstalk between 5-methylcytosine and N6-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in …
Y Tian, H **ao, Y Yang, P Zhang, J Yuan, W Zhang… - Molecular cancer, 2023 - Springer
Background Accumulated evidence highlights the significance of the crosstalk between
epigenetic and epitranscriptomic mechanisms, notably 5-methylcytosine (5mC) and N6 …
epigenetic and epitranscriptomic mechanisms, notably 5-methylcytosine (5mC) and N6 …
Expression profile of immune checkpoint genes and their roles in predicting immunotherapy response
Immune checkpoint genes (ICGs) play critical roles in circumventing self-reactivity and
represent a novel target to develop treatments for cancers. However, a comprehensive …
represent a novel target to develop treatments for cancers. However, a comprehensive …
CD8 T cell score as a prognostic biomarker for triple negative breast cancer
CD8 T cell is an essential component of tumor-infiltrating lymphocytes (TIL) and tumor
immune microenvironment (TIME). Using the xCell CD8 T cell score of whole tumor gene …
immune microenvironment (TIME). Using the xCell CD8 T cell score of whole tumor gene …
Interaction between chronic endometritis caused endometrial microbiota disorder and endometrial immune environment change in recurrent implantation failure
P Chen, P Chen, Y Guo, C Fang, T Li - Frontiers in Immunology, 2021 - frontiersin.org
Objective To investigate the Interaction between chronic endometritis (CE) caused
endometrial microbiota disorder and endometrial immune environment change in recurrent …
endometrial microbiota disorder and endometrial immune environment change in recurrent …
Pan-cancer analysis shows that ALKBH5 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including gliomas
C Wei, B Wang, D Peng, X Zhang, Z Li, L Luo… - Frontiers in …, 2022 - frontiersin.org
Background AlkB homolog 5 (ALKBH5) is a N6-methyladenosine (m6A) demethylase
associated with the development, growth, and progression of multiple cancer types …
associated with the development, growth, and progression of multiple cancer types …