Three-dimensional printing, holograms, computational modelling, and artificial intelligence for adult congenital heart disease care: an exciting future
Congenital heart disease (CHD) is often comprised of complex three-dimensional (3D)
anatomy that must be well understood to assess the pathophysiological consequences and …
anatomy that must be well understood to assess the pathophysiological consequences and …
Mechanisms of Aortic Dilation in Patients With Bicuspid Aortic Valve: JACC State-of-the-Art Review
JF Rodríguez-Palomares, L Dux-Santoy… - Journal of the American …, 2023 - jacc.org
Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …
Wall shear stress predicts aortic dilation in patients with bicuspid aortic valve
Objectives This study sought to assess the predictive value of wall shear stress (WSS) for
colocalized ascending aorta (AAo) growth rate (GR) in patients with bicuspid aortic valve …
colocalized ascending aorta (AAo) growth rate (GR) in patients with bicuspid aortic valve …
High wall shear stress can predict wall degradation in ascending aortic aneurysms: an integrated biomechanics study
Background: Blood flow patterns can alter material properties of ascending thoracic aortic
aneurysms (ATAA) via vascular wall remodeling. This study examines the relationship …
aneurysms (ATAA) via vascular wall remodeling. This study examines the relationship …
Patient-specific bicuspid aortic valve biomechanics: a magnetic resonance imaging integrated fluid–structure interaction approach
Congenital bicuspid aortic valve (BAV) consists of two fused cusps and represents a major
risk factor for calcific valvular stenosis. Herein, a fully coupled fluid–structure interaction (FSI) …
risk factor for calcific valvular stenosis. Herein, a fully coupled fluid–structure interaction (FSI) …
Oxidative stress in genetically triggered thoracic aortic aneurysm: role in pathogenesis and therapeutic opportunities
SS Portelli, BD Hambly, RW Jeremy… - Redox Report, 2021 - Taylor & Francis
Background: The primary objective of this review was to explore the contribution of oxidative
stress to the pathogenesis of genetically-triggered thoracic aortic aneurysm (TAA) …
stress to the pathogenesis of genetically-triggered thoracic aortic aneurysm (TAA) …
[HTML][HTML] Computational study of aortic hemodynamics for patients with an abnormal aortic valve: The importance of secondary flow at the ascending aorta inlet
Blood flow in the aorta is helical, but most computational studies ignore the presence of
secondary flow components at the ascending aorta (AAo) inlet. The aim of this study is to …
secondary flow components at the ascending aorta (AAo) inlet. The aim of this study is to …
The science of BAV aortopathy
FL Presti, DG Guzzardi, C Bancone, PWM Fedak… - Progress in …, 2020 - Elsevier
The aortopathy associated with bicuspid aortic valve (BAV) is an epidemiologically relevant
source of chronic and acute aortic disease (aneurysm and dissection). However, its …
source of chronic and acute aortic disease (aneurysm and dissection). However, its …
4D-flow MRI derived wall shear stress for the risk stratification of bicuspid aortic valve aortopathy: A systematic review
Purpose Current intervention guidelines for bicuspid aortic valve (BAV) associated
ascending aorta (AAo) dilatation are suboptimal predictors of clinical outcome. There is …
ascending aorta (AAo) dilatation are suboptimal predictors of clinical outcome. There is …
Low and oscillatory wall shear stress is not related to aortic dilation in patients with bicuspid aortic valve: a time-resolved 3-dimensional phase-contrast magnetic …
Objective: To assess the relationship between regional wall shear stress (WSS) and
oscillatory shear index (OSI) and aortic dilation in patients with bicuspid aortic valve (BAV) …
oscillatory shear index (OSI) and aortic dilation in patients with bicuspid aortic valve (BAV) …