It is now well known that non-coding RNAs (ncRNAs), rather than protein-coding transcripts,
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …

MicroRNAs (miRNAs) are endogenous non-coding RNAs that contain approximately 22
nucleotides. They serve as key regulators in various biological processes and their …

The recognition of RNA functions beyond canonical protein synthesis has challenged the
central dogma of molecular biology. Indeed, RNA is now known to directly regulate many …

MicroRNAs (miRNAs) are small non-coding RNAs which contribute to the regulation of many
physiological and pathological processes. Conventionally, miRNAs perform their activity in …

Context It is increasingly evident that non–protein-coding regions of the genome can give
rise to transcripts that form functional layers of the cancer genome. One of most abundant …

Glioblastoma with intracranial infiltrative growth remains an incurable disease mainly owing
to existence of blood brain barrier (BBB) and off-target drug toxicity. RNA interference (RNAi) …

2106 Long non-coding RNA and Polycomb: an intricate partnership in cancer biology Cyrinne
Achour1, 2, Francesca Aguilo1, 2 1Wall Page 1 2106 Long non-coding RNA and Polycomb: an …

Despite the recent advances in cancer therapy, triple-negative breast cancers (TNBCs) are
the most relapsing cancer sub-type. It is partly due to their propensity to develop resistance …

MicroRNA (miRNA) is a class of endogenous small non-coding RNA of 18–25 nucleotides
and plays regulatory roles in both physiological and pathological processes. Emerging …

Rhabdomyosarcoma tumor cells resemble differentiating skeletal muscle cells, which unlike
normal muscle cells, fail to undergo terminal differentiation, underlying their proliferative and …