Extracellular vesicles (EVs), including exosomes and microvesicles, are lipid bilayer
particles naturally released from the cell. While exosomes are formed as intraluminal …

A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

This review summarizes the results of clinical trials of cell therapy in patients with heart
failure (HF). In contrast to acute myocardial infarction (where results have been consistently …

Cardiovascular disease (CVD) is the leading cause of death worldwide and is a global
health issue. Traditionally, statistical models are used commonly in the risk prediction and …

Observer-driven pattern recognition is the standard for interpretation of medical images. To
achieve global parity in interpretation, semi-quantitative scoring systems have been …

Although the clinical outcomes of cell therapy trials have not met initial expectations,
emerging evidence suggests that injury-mediated tissue damage might benefit from the …

During the past decades, stem cell‐based therapy has acquired a promising role in
regenerative medicine. The application of novel cell therapeutics for the treatment of …

Introduction Acute myocardial infarction (AMI) remains a leading cause of death in the
United States. The limited capacity of cardiomyocytes to regenerate and the restricted …

Endothelial inflammation plays a crucial role in vascular-related diseases, a leading cause
of global mortality. Among various cellular players, endothelial progenitor cells (EPCs) …

Mesenchymal stem cell (MSC) transplantation after myocardial infarction (MI) has been
shown to effectively limit the infarct area in numerous clinical and preclinical studies …