Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints
them with a variety of inflammatory processes. For example, platelets can act as circulating …

Platelets play a variety of roles in vascular biology and are best recognized as primary
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …

Fibrosis is a major cause of mortality worldwide, characterized by myofibroblast activation
and excessive extracellular matrix deposition. Systemic sclerosis is a prototypic fibrotic …

Regulation of endosomal Toll-like receptor (TLR) responses by the chemokine CXCL4 is
implicated in inflammatory and fibrotic diseases, with CXCL4 proposed to potentiate TLR …

Cardiovascular disease (CVD) is a class of diseases with high disability and mortality rates.
In the elderly population, the incidence of cardiovascular disease is increasing annually …

Systemic sclerosis (SSc) is a severe autoimmune disease that is characterized by vascular
abnormalities, immunological alterations and fibrosis of the skin and internal organs. The …

Platelets, anucleate blood components, represent the major cell type involved in the
regulation of hemostasis and thrombosis. In addition to performing haemostatic roles …

For most frequent respiratory viruses, there is an urgent need for a universal influenza
vaccine to provide cross-protection against intra-and heterosubtypes. We previously …

The severe form of COVID-19 has significant sex disparities, with high fatalities commonly
reported among males than females. The incidence of COVID-19 has also been higher in …