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Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer
Background Due to the limited success in the treatment of lung adenocarcinomas, new
treatment protocols are urgently needed to increase the curability rate and the survival of …
treatment protocols are urgently needed to increase the curability rate and the survival of …
Anti-tumor efficacy and safety of AEV01 in preclinical glioblastoma and hepatocellular carcinoma models
I Biswas, SD Precilla, A Kumar, MM Sekhar… - Scientific Reports, 2025 - nature.com
Glioblastoma (GB) and hepatocellular carcinoma (HCC) are aggressive cancers with poor
prognoses, often leading to less than a year of survival. Therapeutic resistance underscores …
prognoses, often leading to less than a year of survival. Therapeutic resistance underscores …
Ultrastructural and immunohistochemical insights on the anti-glioma effects of a dual-drug cocktail in an in vivo experimental model
Glioma coined as 'butterfly tumor'exhibits intense heterogeneity at the molecular and cellular
levels. Although, Temozolomide exerted a long-ranging and prevailing therapeutic effect …
levels. Although, Temozolomide exerted a long-ranging and prevailing therapeutic effect …
Anti-Tumor Potential of AEV01 in Glioma: In Vitro and Xenograft Model Studies
TS Anitha, I Biswas, A Kumar, MM Sekhar, R Medasani - bioRxiv, 2024 - biorxiv.org
Background Gliomas are difficult to treat with short survival rates despite current therapies.
The need for new treatments is urgent, and orthotopic cell-derived tumor xenograft (CDX) …
The need for new treatments is urgent, and orthotopic cell-derived tumor xenograft (CDX) …