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Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
Noncoding RNA therapeutics—challenges and potential solutions
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
Where should siRNAs go: applicable organs for siRNA drugs
I Ahn, CS Kang, J Han - Experimental & Molecular Medicine, 2023 - nature.com
RNA interference mediated by small interfering RNAs (siRNAs) has been exploited for the
development of therapeutics. siRNAs can be a powerful therapeutic tool because the …
development of therapeutics. siRNAs can be a powerful therapeutic tool because the …
[HTML][HTML] A historical review of brain drug delivery
WM Pardridge - Pharmaceutics, 2022 - mdpi.com
The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
Glioblastoma therapy: Past, present and future
E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …
Although great efforts have been made by clinicians and researchers, no significant …
Clinical translation of gold nanoparticles
Gold nanoparticles display unique physicochemical features, which can be useful for
therapeutic purposes. After two decades of preclinical progress, gold nanoconstructs are …
therapeutic purposes. After two decades of preclinical progress, gold nanoconstructs are …
NIR-II light-driven genetically engineered exosome nanocatalysts for efficient phototherapy against glioblastoma
X Fang, R Gong, D Yang, C Li, Y Zhang… - Journal of the …, 2024 - ACS Publications
Glioblastoma (GBM) poses a significant therapeutic challenge due to its invasive nature and
limited drug penetration through the blood–brain barrier (BBB). In response, here we …
limited drug penetration through the blood–brain barrier (BBB). In response, here we …
Materials engineering strategies for cancer vaccine adjuvant development
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery
Conventional chemotherapy, one of the most widely used cancer treatment methods, has
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …
[HTML][HTML] Applications and safety of gold nanoparticles as therapeutic devices in clinical trials
L Yao, D Bojic, M Liu - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Use of gold nanoparticles (GNPs) in medicine is an emerging field of translational research
with vast clinical implications and exciting therapeutic potential. However, the safety of using …
with vast clinical implications and exciting therapeutic potential. However, the safety of using …