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A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality.
Contextual fear conditioning is a classical laboratory task that tests associative memory
formation and recall. Techniques such as multi-photon microscopy and holographic …
formation and recall. Techniques such as multi-photon microscopy and holographic …
A Model of Place Field Reorganization During Reward Maximization
When rodents learn to navigate in a novel environment, a high density of place fields
emerges at reward locations, fields elongate against the trajectory, and individual fields …
emerges at reward locations, fields elongate against the trajectory, and individual fields …
Single field evolution rule governs the dynamics of representational drift in mouse hippocampal dorsal CA1 region
How the brain reconciles dynamism with stability to balance learning and reliable memory
storage has not yet been fully understood. To address the critical question, we longitudinally …
storage has not yet been fully understood. To address the critical question, we longitudinally …
Months-long stability of the head-direction system
SS Carrasco, G Viejo, A Peyrache - bioRxiv, 2024 - biorxiv.org
Spatial orientation is a universal ability that allows animals to navigate their environment. In
mammals, the head-direction (HD) system is an essential component of the brain's …
mammals, the head-direction (HD) system is an essential component of the brain's …
Deep learning-based location decoding reveals that across-day representational drift is better predicted by rewarded experience than time
Neural representations of space in the hippocampus and related brain areas change over
timescales of days-weeks, even in familiar contexts and when behavior appears stable. It is …
timescales of days-weeks, even in familiar contexts and when behavior appears stable. It is …