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Hantavirus in humans: a review of clinical aspects and management
Hantavirus infections are part of the broad group of viral haemorrhagic fevers. They are also
recognised as a distinct model of an emergent zoonotic infection with a global distribution …
recognised as a distinct model of an emergent zoonotic infection with a global distribution …
[HTML][HTML] Neutralization determinants on Poxviruses
Smallpox was a highly contagious disease caused by the variola virus. The disease affected
millions of people over thousands of years and variola virus ranked as one of the deadliest …
millions of people over thousands of years and variola virus ranked as one of the deadliest …
Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody
Emerging rodent-borne hantaviruses cause severe diseases in humans with no approved
vaccines or therapeutics. We recently isolated a monoclonal broadly neutralizing antibody …
vaccines or therapeutics. We recently isolated a monoclonal broadly neutralizing antibody …
Antigenic map** and functional characterization of human New World hantavirus neutralizing antibodies
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to
humans by aerosolized excreta or, in rare cases, person-to-person contact. While infections …
humans by aerosolized excreta or, in rare cases, person-to-person contact. While infections …
[HTML][HTML] Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlap** regions on glycoprotein GP38
OS Shin, SR Monticelli, CK Hjorth, V Hornet, M Doyle… - Cell reports, 2024 - cell.com
Crimean-Congo hemorrhagic fever virus can cause lethal disease in humans yet there are
no approved medical countermeasures. Viral glycoprotein GP38, exclusive to Nairoviridae …
no approved medical countermeasures. Viral glycoprotein GP38, exclusive to Nairoviridae …
Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody
R Stass, TB Engdahl, NS Chapman, RM Wolters… - Nature …, 2023 - nature.com
Rodent-borne hantaviruses are prevalent worldwide and upon spillover to human
populations, cause severe disease for which no specific treatment is available. A potent …
populations, cause severe disease for which no specific treatment is available. A potent …
Characterization of a panel of cross-reactive Hantavirus Nucleocapsid protein-specific monoclonal antibodies
A Avižinienė, I Kučinskaitė-Kodzė… - Viruses, 2023 - mdpi.com
Hantaviruses are emerging pathogens with a worldwide distribution that can cause life-
threatening diseases in humans. Monoclonal antibodies (MAbs) against hantavirus …
threatening diseases in humans. Monoclonal antibodies (MAbs) against hantavirus …
The Adaptive Immune Response against Bunyavirales
The Bunyavirales order includes at least fourteen families with diverse but related viruses,
which are transmitted to vertebrate hosts by arthropod or rodent vectors. These viruses are …
which are transmitted to vertebrate hosts by arthropod or rodent vectors. These viruses are …
Phase 1 clinical trial of Hantaan and Puumala virus DNA vaccines delivered by needle-free injection
Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic zoonoses found in Asia
and Europe, respectively. We conducted a randomized Phase 1 clinical trial of individual …
and Europe, respectively. We conducted a randomized Phase 1 clinical trial of individual …
A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies
M Rissmann, D Noack, TM Spliethof, VP Vaes… - PLoS …, 2025 - journals.plos.org
Orthohantaviruses are emerging zoonotic viruses that can infect humans via the respiratory
tract. There is an unmet need for an in vivo model to study infection of different …
tract. There is an unmet need for an in vivo model to study infection of different …