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[HTML][HTML] Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
Small RNAs, large networks: posttranscriptional regulons in gram-negative bacteria
Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …
Biofilms by bacterial human pathogens: Clinical relevance-development, composition and regulation-therapeutical strategies
A Schulze, F Mitterer, JP Pombo, S Schild - Microbial Cell, 2021 - pmc.ncbi.nlm.nih.gov
Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …
facilitating many infectious disease processes. In this review we will focus on bacterial …
An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae
Small regulatory RNAs (sRNAs) acting in concert with the RNA chaperone Hfq are prevalent
in many bacteria and typically act by base-pairing with multiple target transcripts. In the …
in many bacteria and typically act by base-pairing with multiple target transcripts. In the …
The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation
M Condinho, B Carvalho, A Cruz, SN Pinto… - FEBS Open …, 2023 - Wiley Online Library
Biofilms provide an ecological advantage against many environmental stressors, such as pH
and temperature, making it the most common life‐cycle stage for many bacteria. These …
and temperature, making it the most common life‐cycle stage for many bacteria. These …
Phenotypic heterogeneity in bacterial quorum sensing systems
V Bettenworth, B Steinfeld, H Duin, K Petersen… - Journal of Molecular …, 2019 - Elsevier
Quorum sensing is usually thought of as a collective behavior in which all members of a
population partake. However, over the last decade, several reports of phenotypic …
population partake. However, over the last decade, several reports of phenotypic …
Salicylic acid stabilizes Staphylococcus aureus biofilm by impairing the agr quorum-sensing system
C Dotto, A Lombarte Serrat, M Ledesma, C Vay… - Scientific Reports, 2021 - nature.com
Salicylic acid (SAL) has recently been shown to induce biofilm formation in Staphylococcus
aureus and to affect the expression of virulence factors. This study was aimed to investigate …
aureus and to affect the expression of virulence factors. This study was aimed to investigate …
Regulatory small RNA Qrr2 is expressed independently of sigma factor-54 and can function as the sole Qrr small RNA to control quorum sensing in Vibrio …
JG Tague, J Hong, SS Kalburge… - Journal of bacteriology, 2022 - journals.asm.org
Bacterial cells alter gene expression in response to changes in population density in a
process called quorum sensing (QS). In Vibrio harveyi, LuxO, a low-cell-density activator of …
process called quorum sensing (QS). In Vibrio harveyi, LuxO, a low-cell-density activator of …
RNA-mediated control of cell shape modulates antibiotic resistance in Vibrio cholerae
N Peschek, R Herzog, PK Singh, M Sprenger… - Nature …, 2020 - nature.com
Vibrio cholerae, the cause of cholera disease, exhibits a characteristic curved rod
morphology, which promotes infectivity and motility in dense hydrogels. Periplasmic protein …
morphology, which promotes infectivity and motility in dense hydrogels. Periplasmic protein …
Quorum sensing going wild
The first discovered and well-characterized bacterial quorum sensing (QS) system belongs
to Vibrio fischeri, which uses N-acyl homo-serine lactones (AHLs) for cell-cell signaling. AHL …
to Vibrio fischeri, which uses N-acyl homo-serine lactones (AHLs) for cell-cell signaling. AHL …