Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …

Long non-coding RNAs (lncRNAs) outnumber protein-coding transcripts, but their functions
remain largely unknown. In this Review, we discuss the emerging roles of lncRNAs in the …

Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …

Breast cancer affects millions of women each year. Despite recent advances in targeted
treatments breast cancer remains a significant threat to women's health. In recent years the …

Long non-coding RNAs (lncRNAs), a group of non-protein coding RNAs with lengths of
more than 200 nucleotides, exert their effects by binding to DNA, mRNA, microRNA, and …

Eukaryotic genomes are prevalently transcribed into many types of RNAs that translate into
proteins or execute gene regulatory functions. Many RNAs associate with chromatin directly …

Given their tumor-specific and stage-specific gene expression, long non-coding RNAs
(lncRNAs) have demonstrated to be potential molecular biomarkers for diagnosis …

Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer with poor
patient outcomes, highlighting the unmet clinical need for targeted therapies and better …